Results 51 to 60 of about 263,365 (240)
Advanced Science, EarlyView.This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir +7 more
wiley +1 more source
Replacing CCT with “best value” [PDF]
, 1999 Professor Christopher Bovis (University of Central Lancashire) assesses the concept of best value in delivering public services, following the demise of the compulsory competitive tendering (CCT) regime. He compares it with its predecessor and elaborates
Bovis, Christopher H.
core
Effect of lattice mismatch-induced strains on coupled diffusive and displacive phase transformations
, 2006 Materials which can undergo slow diffusive transformations as well as fast displacive transformations are studied using the phase-field method. The model captures the essential features of the time-temperature-transformation (TTT) diagrams, continuous ...
J. D. Gunton +6 more
core +1 more source
The impact of conditional cash transfers on health outcomes and use of health services in low and middle income countries. [PDF]
, 2009 BACKGROUND: Conditional cash transfers (CCT) provide monetary transfers to households on the condition that they comply with some pre-defined requirements.
Haines, Andy +2 more
core +1 more source
Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques
Advanced Science, EarlyView.Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang +12 more
wiley +1 more source
Advanced Science, EarlyView.This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng +7 more
wiley +1 more source
EVOLUCIÓN DE LAS CONDICIONES SOCIOECONÓMICAS DE LOS HOGARES EN EL PROGRAMA OPORTUNIDADES
El Trimestre Económico, 2013 Este artículo muestra evidencia empírica que permite comprender cómo evolucio-na el bienestar de los hogares beneficiarios del programa de transferencias mone-tarias condicionadas Oportunidades en el corto y mediano plazos.
Raymundo M. Campos-Vázquez +3 more
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Advanced Science, EarlyView.A new cerebrocortical organoid model using isogenic hiPSCs with familial Alzheimer's mutations recapitulates key AD features, including amyloid‐beta and phospho‐Tau aggregation, neuronal hyperexcitability, and synapse loss. Single‐cell RNA‐seq reveals aberrant pathways in excitatory and inhibitory neurons.
Sergio R. Labra +23 more
wiley +1 more source
Advanced Human Immune Cell‐Organoid Co‐Cultures for Functional Testing of Cancer Nanovaccines
Advanced Science, EarlyView.Pancreatic ductal adenocarcinoma remains difficult to treat. We establish an organoid–immune co‐culture using patient‐derived organoids and matched T‐cells to assess cancer vaccines. A mesothelin‐targeted nanovaccine activates antigen‐specific T‐cells, increases IFN‐γ, and targets MSLN+ organoids.
Nathalia Ferreira +18 more
wiley +1 more source
ANÁLISE PRELIMINAR DA QUALIDADE DAS ÁGUAS DO AQUÍFERO LIVRE NO MUNICÍPIO DE SÃO JOÃO DA BARRA, RJ
Revista Águas Subterrâneas, 2015 O presente trabalho foi realizado no município de São João da Barra (SJB), Norte do Estado do Rio de Janeiro que se localiza na Bacia Sedimentar de Campos, e representa o maior potencial hídrico subterrâneo do Estado.
Flavio Costa de Cerqueira +5 more
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