Results 61 to 70 of about 687,295 (324)
Protection and improvement of the environment, especially preservation and protection of the land, has become one of the most important problems of the modern world today.
Marija Kojić+2 more
doaj +1 more source
OP data on CD for mean opacities and radiative accelerations [PDF]
All monochromatic opacity data from the Opacity Project (OP), together with all codes required for the calculation of mean opacities and radiative accelerations for any required chemical mixture, temperature and mass-density, are being put on a 700 Mb CD which will be made generally available.
arxiv +1 more source
A heuristic search algorithm for discovering large Condorcet domains [PDF]
The study of large Condorcet domains (CD) has been a significant area of interest in voting theory. In this paper, our goal is to search for large CDs that are hitherto unknown. With a straightforward combinatorial definition, searching for large CDs is naturally suited for algorithmic optimisations.
arxiv
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Properties for CD Inequalities with Unbounded Laplacians [PDF]
The CD equalities were introduced to imply the gradient estimate of laplace operator on graphs. This article is based on the unbounded Laplacians, and finally concludes some equivalent properties of the CD(K,$\infty$)and CD(K,n).
arxiv
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Assessment of Pb, Cd, and Zn in Isfahan’s air dust during 2015-2017 (A case study: North, West, and East Stations of Isfahan) [PDF]
The present study aimed to measure the heavy metals existing in Isfahan’s dust at three stations during 2015-2017. This study was carried out in three stations located at north and northwest, west and southwest, and east and southeast parts of Isfahan ...
Amir Hossein Baghaie, Abbas Ahmadi
doaj +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source