Results 41 to 50 of about 1,681,353 (346)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Bioscience Journal, 2018 Usually, weak inorganic acids have been used to disperse collagen as green solvents for fabricating kinds of biomaterials all the time. However, it is an open question how much the dissolving process preserves or alters the native structure of collagen ...
Yuanyuan Zhou +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Unraveling Deep-Ocean Connections to Climate with Deep-Sea Coral Records of Radiocarbon and Cd/Ca [PDF]
, 2006 We generated records of radiocarbon and trace metals in deep-sea corals to investigate the role of the deep ocean during episodes of rapid environmental change.
Eltgroth, Selene Farrell
core +1 more source
Determination of Soil Cadmium Threshold for Potato
Frontiers in Environmental Science, 2022 In this study, pot experiments were conducted to investigate the characteristics of Cd transfer to potato tubers from two types of soil. The results showed that the Log-normal and Burr III functions can be used to determine the sensitivity of different ...
Wei Li, Xue He, Jie Zhang, Ke Liu
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
, 2023 Introduction of African Initiative for Combating Desertification to Strengthen Resilience to Climate Change in the Sahel and the Horn of Africa (AI-CD) and activities in Nigeria to combat ...
Secreatariat, AI-CD
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
AI-CD Mali Short Film (Long version)
, 2023 Introduction of activities to combat desertification in Mali by AI-CD Focal Point in ...
Secreatariat, AI-CD
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source