Results 41 to 50 of about 3,739,900 (282)
, 2003 Cadmium (Cd) is a well-known nephrotoxic environmental contaminant but there are indications that the developing nervous system might be even more sensitive to Cd than the kidneys in adults.
Eklund, Gunilla
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Bioscience Journal, 2018 Usually, weak inorganic acids have been used to disperse collagen as green solvents for fabricating kinds of biomaterials all the time. However, it is an open question how much the dissolving process preserves or alters the native structure of collagen ...
Yuanyuan Zhou +4 more
doaj +1 more source
Determination of Soil Cadmium Threshold for Potato
Frontiers in Environmental Science, 2022 In this study, pot experiments were conducted to investigate the characteristics of Cd transfer to potato tubers from two types of soil. The results showed that the Log-normal and Burr III functions can be used to determine the sensitivity of different ...
Wei Li, Xue He, Jie Zhang, Ke Liu
doaj +1 more source
The English riots and tough sentencing [PDF]
, 2011 This article appeared on the OUP Blog Website on 7 September 2011. The final version can be accessed at the link below.The riots which occurred in London and several other major cities early in August have provoked a debate, still on-going, around a ...
Piper, CD
core
Carbohydrate Intake in the Etiology of Crohn's Disease and Ulcerative Colitis [PDF]
, 2014 Background: Diet may have a role in the etiology of inflammatory bowel disease. In previous studies, the associations between increased intakes of carbohydrates, sugar, starch, and inflammatory bowel disease are inconsistent.
Abraham +83 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
, 2004 Assessment is not only a major practice tool for social workers and medical professionals but also a gatekeeper. It operates to open or close the way for intervention or treatment for a child or his family in the same way that the Crown Prosecutor ...
Piper, CD
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source