Results 61 to 70 of about 1,288,874 (296)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
The Objective was to study changes in serum C-reactive protein (CRP) concentration in the postoperative period in patients with Crohn’s disease (CD), as well as to substantiate and develop an algorithm for using predictors of inflammation to prevent the ...
A. A. Kamanin +5 more
doaj +1 more source
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
DeepDive: A deep dive into the physics of the first massive quiescent galaxies in the Universe
We present the DeepDive program, in which we obtained deep (1 − 3 hours) JWST/NIRSpec G235M/F170LP spectra for ten primary massive (log(M★/M⊙) = 10.8 − 11.5) quiescent galaxies at z ∼ 3 − 4.
Ito K. +28 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The problem of the formation of metabolic syndrome in children is becoming more and more urgent every year, which is associated with excess nutrition, physical inactivity, increased psycho-emotional stress, therefore, timely identification of immune and ...
N. V. Zaitseva +4 more
doaj +1 more source

