Results 71 to 80 of about 687,295 (324)
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
The priority of this study was to investigate how selenium influences toxicity of Cd, Zn, Cu and Pb when the metals appear in the hydroponic solution in pairs. As a model subject mustard seedlings (Sinapis alba L.) were used.
A. Fargašová+2 more
doaj +1 more source
Landmine contamination is a vital contributor to long-lasting destructive effects on terrestrial ecosystem. Libya has experienced severe landmine impacts involving soil contamination with hazardous heavy metals.
Manal Al-Traboulsi, Mohamed A. Alaib
doaj +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
Heavy metal composition of maize and tomato grown on contaminated soils
The study investigated the level of heavy metal contamination in plants {maize (Zea mays) and tomato (Solanum lycopersicum L.)} from thirty soil samples of three locations (Epe, Igun and Ijana) in the Ilesha gold mining area, Osun State, Nigeria.
Adekiya A.O.+3 more
doaj +1 more source
Various single extractants (EDTA, DTPA, CaCl2, NaNO3 and NH4NO3) and the first step of Community Bureau of Reference (BCR1) method were used to evaluate the immobilization of Cd in contaminated acidic paddy soil by different amendments.
Q.H. Zhu+8 more
doaj +1 more source
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
CD-split and HPD-split: efficient conformal regions in high dimensions [PDF]
Conformal methods create prediction bands that control average coverage assuming solely i.i.d. data. Although the literature has mostly focused on prediction intervals, more general regions can often better represent uncertainty. For instance, a bimodal target is better represented by the union of two intervals.
arxiv
Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal+8 more
wiley +1 more source
Irreducible character degrees and normal subgroups [PDF]
Let N be a normal subgroup of a finite group G and consider the set cd(G|N) of degrees of irreducible characters of G whose kernels do not contain N. A number of theorems are proved relating the set cd(G|N) to the structure of N. For example, if N is solvable, its derived length is bounded above by a function of |cd(G|N)|. Also, if |cd(G|N)| is at most
arxiv