Results 171 to 180 of about 15,811 (198)

Electrochemical Screening of Peptides for Targeting CD13

ECS Meeting Abstracts, 2013
Abstract not Available.
Sanela Martic, Kamaljit Kaur, Rania Soudy   +2 more
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cd13 controls myeloid cell-cell fusion

The Journal of Immunology, 2023
Abstract Macrophages have the ability to undergo phenotypic and functional changes in response to microenvironmental cues. One such change is the formation of multinucleated giant cells (MGCs) via intercellular fusion triggered by certain bacterial or parasitic infections or implantation of medical devices that induces deleterious MGC ...
Mallika Ghosh, Fraser Mcgurk, Linda Shapiro   +2 more
openaire   +1 more source

Expression of aminopeptidase N/CD13 in human ovarian cancers

International Journal of Gynecological Cancer, 2006
Aminopeptidase N/CD13 (EC 3.4.11.2) is suggested to play a role in cancer cells invasion, and its activity can be inhibited using specific inhibitors. CD13 inhibitors evoke apoptosis of CD13-positive cancer cells. However, expression of CD13 has not been described in specimens obtained from ovarian carcinomas. Thus, in the present study, the expression
P, Surowiak, M, Drag, V, Materna, S, Suchocki, R, Grzywa, M, Spaczyński, M, Dietel, J, Oleksyszyn, M, Zabel, H, Lage   +9 more
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Progress in the Development of Aminopeptidase N (APN/CD13) Inhibitors

Current Medicinal Chemistry-Anti-Cancer Agents, 2005
Aminopeptidase N (APN; CD13) is a member of zinc-containing ectoenzymes family involved in the degradation of neutral or basic amino acids (Ala>Phe>Leu>Gly) from N-terminal of bioactive peptides and amide or arylamide derivatives of amino acids. The expression of APN being up regulated has been implicated in the pathogenesis of a variety of diseases ...
Wenfang, Xu, Qianbin, Li
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CD4+, CD33-, CD13-, CD14-Acute Monoblastic Leukaemia

Acta Haematologica, 2009
We report a case of acute monoblastic leukaemia in which the expression of the CD4 antigen occured in the absence of myeloid and monocytic lineage specific markers. Unexpected marker profiles have biological and diagnostic implications and we also suggest that the inappropriate expression of the CD4 antigen may be implicated in the poor prognosis of ...
E H, Lombard, E P, Mansvelt
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Prostasome to sperm transfer of CD13/aminopeptidase N (EC 3.4.11.2)

Biochimica et Biophysica Acta (BBA) - General Subjects, 1997
Prostasomes are membranous vesicles (150-200 nm in diameter) that are present in human semen. They are secreted by the prostate gland and contain large amounts of cholesterol, sphingomyelin and Ca2+. In addition, some of their proteins are enzymes. Prostasomes enhance the motility of ejaculated spermatozoa and are involved in a number of additional ...
ARIENTI, Giuseppe, CARLINI E., VERDACCHI R., COSMI E. V., PALMERINI, Carlo Alberto   +4 more
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Aminopeptidase N/CD13 and haematopoietic cells

Haema, 2003
Several cell-surface antigens defined by the cluster of differentiation (CD) nomenclature have been defined as proteins with enzymatic activity. An important example is CD13, aminopeptidase N (APN ; EC 3.4.11.2). It is a zinc-dependent membrane-bound ectopeptidase that cleaves N-terminal neutral amino acids of various peptides.
Gabrilovac, Jelka, Breljak, Davorka, Boranić, Milivoj   +2 more
openaire   +1 more source

CD13

AfCS-Nature Molecule Pages, 2005
Wolfgang Schacke, Nenad Petrovic, Linda Shapiro   +2 more
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[CD13- and CD33-negative acute myelocytic leukemia (FAB classification; M2) with morphological changes and CD13 expression on recurrence].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2001
A 42-year-old man was diagnosed as having acute myelocytic leukemia in July 1998. The leukemic cells tended to be differentiated, and on the basis of positive peroxidase staining, this case was considered to be AML (M2) according to the FAB classification.
Y, Aoyama, T, Yamane, H, Kanashima, Y, Takeoka, K, Koh, Y, Nakao, R, Yamamura, H, Nakamae, K, Ohta, T, Inoue, M, Hino, N, Tatsumi   +11 more
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CD10 and CD13 expression on cultured human keratinocytes

2002
Membrane aminopeptidases expressed on cells of hematopoietic origin are involved in specific immune response (antigen processing and presentation) and in inflammation (cleavage of some cytokines and chemokines). Keratinocytes, epidermal skin cells, also secrete cytokines and participate in skin immune response.
Zekušić, Marija, Breljak, Davorka, Martin-Kleiner, Irena, Čupić, Barbara, Gabrilovac, Jelka, Boranić, Milivoj, Jakić-Razumović, Jasminka   +6 more
openaire   +1 more source