Results 171 to 180 of about 131,028 (295)

Association of Monocyte Subsets with Carotid Artery Stenosis Severity. [PDF]

Medicina (Kaunas)
Deniz L, Sonmez D, Cakir MS, Ozgur E, Akdogan O, Adiyaman Z, Aral H.   +6 more
europepmc   +1 more source

Microglia Ablation and Downstream Effects in the Cerebrospinal Fluid Proteome

PROTEOMICS, EarlyView.
ABSTRACT Disease‐related activation of glial cells leads to changes in the cerebrospinal fluid (CSF) proteome. However, assigning such protein changes to their cellular origins is often difficult. Here, we used microglia (and macrophage) depletion in mice to identify CSF proteins of microglial origin.
Sinja Buchner, Sihui Song, Stephan A. Müller, Yun Chen, Samira Parhizkar, Stefan F. Lichtenthaler, David M. Holtzman, Mathias Jucker, Stephan A. Kaeser   +8 more
wiley   +1 more source

CD14 Gene [PDF]

, 2020
openaire   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Altered Distribution of CD14⁺ Macrophages and Reduced ROS Activity in Preeclamptic Placentas. [PDF]

Am J Reprod Immunol
Donis-Maturano L, Flores-Colque JY, Calderon-Amador J, Moreno-Corona NC, Pérez-Luna OD, López-Ortega O.   +5 more
europepmc   +1 more source

CD14 Positive [PDF]

, 2020
openaire   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Immunoids: Building immunocompetent organoids from human pluripotent stem cells. [PDF]

Cell Stem Cell
O'Hern C, Miller Z, Dionise M, Kulkarni SH, Contag CH, Aguirre A.   +5 more
europepmc   +1 more source

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

Rheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues, Helena Margarida de Miranda Lemos Romão Donato, Soraia Raquel Loureiro Azevedo, Luís Miguel da Silva Pires, Luís Pedro Bolotinha de Sousa Inês, Manuel Augusto Nunes Vicente Passos Morgado, Ana Filipa de Sousa Pestana Mourão   +6 more
wiley   +1 more source

Induction of dysfunctional CD14^lowCD16^- monocytes in acute COVID-19 infection. [PDF]

Front Immunol
Ebrahimnezhaddarzi S, Altermatt A, Kek H, Zhou J, Boo I, McMahon JH, Gardiner BJ, Sacks-Davis R, Drummer HE, Jaworowski A, Hearps AC.   +10 more
europepmc   +1 more source