Results 111 to 120 of about 113,188 (264)

Comparison of Tissue Preparations to Identify and Phenotype T Cells in Human Colorectal Tumor Tissue

Cytometry Part A, EarlyView.
ABSTRACT Archived patient samples (e.g., formalin‐fixed paraffin embedded (FFPE) tissue blocks, cryoembedded tissue blocks, and frozen whole tissue samples) are a source of immune information for which corresponding patient data is often collected.
Justin F. Tirados, Sonya Fenton, Helen M. McGuire, Joanna M. Roberts, Kirsten A. Ward‐Hartstonge, Roslyn A. Kemp   +5 more
wiley   +1 more source

Ultrasound priming gated by solid tumor hallmarks to guide CAR-T therapy. [PDF]

Sci Adv
Guo T, Zhu Z, Qu Y, Yu X, Zhu L, Wang Y, Liu K, Cui J, Dong X, Yoon CW, Kilic CY, He P, Gou S, Zeng Y, Datta P, Zhou Q, Xu H, Puri IK, Liu L, Shen K, Wang Y.   +20 more
europepmc   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source

CD19 Gene [PDF]

, 2020
openaire   +1 more source

Truncated CD19 as a selection marker for the isolation of stem cell-derived β-cells

Disease Models & Mechanisms
Luo Ting Huang, Raymond Jun-rui Gao, Dahai Zhang, Cuilan Nian, Willem Martzke, A. M. James Shapiro, Tatsuya Kin, Yaser Tahamtani, Francis C. Lynn   +8 more
doaj   +1 more source

DP028 | CD19.CAR-T CELL-DERIVED EXTRACELLULAR VESICLES RETAIN CAR EXPRESSION AND EXHIBIT CYTOTOXIC ACTIVITY AGAINST LEUKEMIC CELLS, SUPPORTING THEIR ROLE IN ANTITUMOR THERAPY.

Haematologica
CAR-T cell therapy has revolutionized the treatment of hematologic malignancies. Nevertheless, significant challenges remain, particularly concerning its severe adverse effects. Extracellular vesicles (EVs) emerged as promising therapeutic agents due to
P. Lanuti, F. Guardalupi, G. Corradi, R. Florio, D. Brocco, S. Veschi, E. Pennese, D. De Bellis, F. D’ascanio, A. Piro, L. De Lellis, P. Simeone, M. C. Cufaro, S. Pilato, I. D’amario, I. Villanova, B. Di Francesco, L. Di Re, F. Verginelli, D. Pieragostino, P. Salutari, F. Colasante, A. Natale, M. V. Mattioli, A. Fontana, R. Giancola, B. Fabi, S. Baldoni, S. Santarone, F. Restuccia, N. Tinari, P. Del Boccio, A. Cama, M. Di Ianni   +33 more
doaj  

Establishment of pediatric reference ranges for circulating naïve and memory T and B cell subsets guided by the human immunophenotyping consortium standardization initiative: A large, single center U.S. experience

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Our knowledge of the immune system continues to expand at a rapid pace, and this coupled with technological advances now enables us to interrogate both the breadth and the depth of the immune response at levels without precedent. This has also facilitated rapidly integrating some of this carefully vetted knowledge into clinical practice ...
Aaruni Khanolkar, Aisha Ahmed
wiley   +1 more source

CD19 Positive [PDF]

, 2020
openaire   +1 more source

Dual-target CAR-T cell therapy: latest updates from the 2025 ASH annual meeting. [PDF]

Exp Hematol Oncol
Feng S, Kong R, Xiao L, Zhou X.
europepmc   +1 more source

DinoFlow: Self‐supervised pretraining in flow cytometry enables accurate detection of common hematopathological disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Flow cytometry is an essential component of routine hematological lab testing. Many computational methods have been proposed for the analysis of flow cytometry data, but most have focused on supervised learning for just one or a few specific disorders.
Brendan O'Fallon, Muir Morrison, Mattia Medina Grespan, Nicholas C. Spies, David P. Ng   +4 more
wiley   +1 more source