Results 121 to 130 of about 113,188 (264)

Folate receptor beta targeting of tumor-associated macrophages improves lymphoma cell responses to CD19 CAR T cells. [PDF]

Hemasphere
Kalander K, Oksa K, Sorri S, Monzo H, Leivonen SK, Ojala PM, Leppä S.   +6 more
europepmc   +1 more source

Regulatory challenges of personalized medicine in the real world: are the right patients being treated with CD19-targeting CAR T-cells? [PDF]

EMBO Mol Med
Sebe A, Hernani R, Müller-Berghaus J.
europepmc   +1 more source

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana, Ernest Musekwa, Erica‐Mari Nell, Zivanai Cuthbert Chapanduka   +3 more
wiley   +1 more source

Novel Noninvasive Broad‐Spectrum Infrared Treatment of Ulcerative Colitis by Modulating T‐Cell Relocation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen, Jiangtao Zhao, Bohan Jia, Zhigang Ren, Ranran Sun, Liwen Liu, Ding Zhang, Yanqiu Fu, Jia Yu, Shen Shen, Fujun Miao, Zaimei Huang, Ruixia Guo, Peng Zhang, Zujiang Yu, Guosheng Shao   +15 more
wiley   +1 more source

B7 homolog 3-targeted CAR-T cells secreting EGFR T-cell engagers for improved control of glioblastoma progression. [PDF]

Mol Biomed
Zhang Z, Yang N, Zeng H, Chen Y, Lu H, Xu L, Wang Z, Wang G, Zhou L, Tong A.   +9 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

CD19 Negative [PDF]

, 2020
openaire   +1 more source

Human CART22.19 therapy in refractory pediatric B-ALL: insights from a named-patient cohort. [PDF]

J Immunother Cancer
Mast AS, Lang P, Schlegel P, Calkoen FG, Atar D, Scheuermann S, Klein S, Braun C, Schinle F, Schmidt M, Hensen L, Ebinger M, Döring M, Schäfer JF, Schulte J, Bethge WA, Lengerke C, Alahmari B, Hu P, Schneider D, Orentas RJ, Handgretinger R, Seitz CM.   +22 more
europepmc   +1 more source

Dietary fiber‐based oral nanovaccine promotes gut‐to‐nose trafficking of regulatory cells and drives antigen‐specific tolerance to relieve airway allergy

iMeta, EarlyView.
Current therapies for allergic rhinitis primarily provide symptomatic relief but fail to establish durable antigen‐specific immune tolerance. Here, we developed an oral nano‐dietary fiber (NDF) platform that integrates allergen delivery with microbiota‐driven immunomodulation, using dextran as both an antigen carrier and a fermentable substrate for ...
Yuting Qin, Zeming Wang, Yuru Zong, Zefang Lu, Junxiu Liu, Ruifang Zhao, Guangjun Nie, Hanqing Chen   +7 more
wiley   +1 more source

APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans. [PDF]

Proc Natl Acad Sci U S A
Moris Amro E, Gkougkousis C, Seebass JG, Telioglu I, Bakr A, Lorenzo JP, Abolhassani H, Altenhofen J, Berntson L, Ruf S, Hammarström L, Pan-Hammarström Q, Imbusch CD, Papavasiliou FN.   +13 more
europepmc   +1 more source