Results 121 to 130 of about 15,620 (207)

CD1a and skin T cells: a pathway for therapeutic intervention

Clinical and Experimental Dermatology
Abstract The CD1 and MR1 protein families present lipid antigens and small molecules to T cells, complementing well-studied major histocompatibility complex–peptide mechanisms. The CD1a subtype is highly and continuously expressed within the skin, most notably on Langerhans cells, and has been demonstrated to present self and foreign ...
Ye, John H, Chen, Yi-Ling, Ogg, Graham
openaire   +2 more sources

Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency

Frontiers in Immunology
IntroductionExosome-enriched small extracellular vesicles (sEVs) are nanosized organelles known to participate in long distance communication between cells, including in the skin.
Adrian Kobiela, Weronika Hewelt-Belka, Joanna E. Frąckowiak, Natalia Kordulewska, Lilit Hovhannisyan, Aleksandra Bogucka, Rachel Etherington, Artur Piróg, Irena Dapic, Susanne Gabrielsson, Susanne Gabrielsson, Sara J. Brown, Graham S. Ogg, Danuta Gutowska-Owsiak, Danuta Gutowska-Owsiak   +14 more
doaj   +1 more source

Reformed Ant-CD1a Monoclonal Antibody Synthesis by Molecular Genetic Method

, 2008
Purpose: CD1a is known to present lipid antigens and observed in various diseases. Anti-CD1a monoclonal antibody can be used to treat and diagnose for a lot of disorders.
오승환
core  

αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands

, 2015
A central paradigm in αβ T cell–mediated immunity is the simultaneous co-recognition of antigens and antigen-presenting molecules by the αβ T cell antigen receptor (TCR). CD1a presents a broad repertoire of lipid-based antigens.
Annemieke de Jong, Keller, Andrew N., Daniel G Pellicci, Stephanie Gras, Tan-Yun Cheng, Jamie Rossjohn, Richard W Birkinshaw, Sandoval-Romero, Maria, Moody, D. Branch, Godfrey, Dale I., Adam P Uldrich, D Branch Moody, Dale I Godfrey, Andrew N Keller, Cheng, Tan-Yun, Gras, Stephanie, Rossjohn, Jamie, Uldrich, Adam P., Maria Sandoval-Romero, Pellicci, Daniel G., Birkinshaw, Richard W., de Jong, Annemieke   +21 more
core   +1 more source

CD1A Positive [PDF]

, 2020
openaire   +1 more source

CD1A wt Allele [PDF]

, 2020
openaire   +1 more source

Possible Mechanism of Action of CD1a Antigens

Journal of Investigative Dermatology, 1990
Hanau, Daniel, Schmitt, Didier, Bieber, Thomas, Schmitt, Daniel, Cazenave, Jean-Pierre   +4 more
openaire   +2 more sources

GM-CSF-Independent CD1a Expression in Epidermal Langerhans Cells: Evidence from Human CD1A Genome-Transgenic Mice [PDF]

Journal of Investigative Dermatology, 2012
Kobayashi, Chisa, Shiina, Takashi, Tokioka, Atsuko, Hattori, Yuki, Komori, Takaya, Kobayashi-Miura, Mikiko, Takizawa, Toshihiro, Takahara, Kazuhiko, Inaba, Kayo, Inoko, Hidetoshi, Takeya, Motohiro, Dranoff, Glenn, Sugita, Masahiko   +12 more
openaire   +2 more sources

Hepatobiliary langerhans cell histiocytosis mimicking Caroli syndrome and recurring in a liver allograft. [PDF]

Front Med (Lausanne)
Hu T, Wang C, Liu C, Sun J.
europepmc   +1 more source

Coinfection of Leprosy and American Cutaneous Leishmaniasis: A Case Report From Ceará, Brazil. [PDF]

Case Rep Med
Neto MPL, Fernandes JO, Ferraz ACC, Marelli JGA, de Lima MAP, da Silva CGL, Kerr LRFS, Gurgel RQ.   +7 more
europepmc   +1 more source