Results 221 to 230 of about 98,309 (302)

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source

Economic value of anti-CD20 therapies in multiple sclerosis: a systematic review of cost-effectiveness studies. [PDF]

Ther Adv Neurol Disord
Heinemann J, Zirkel M, Schoeffski O, Dersch R, Wiendl H.   +4 more
europepmc   +1 more source

Congenital aleukemic leukemia cutis mimicking infantile hemangioma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ana Clara Maia Palhano, Fábio Augusto Peroni Garcia, Thais Kohatsu Yanase, Luciana Paula Samorano, Maria Cecilia Rivitti‐Machado, Zilda de Najjar Prado Oliveira   +5 more
wiley   +1 more source

CD49a expression defines a metabolically robust, cytokine‐biased liver NK cell subset in rhesus macaques during lentivirus infection

Immunology &Cell Biology, EarlyView.
Liver‐resident NK cells (CD49a+ NK cells) in rhesus macaques display distinct activating receptor and metabolic markers enhanced phenotype compared with hepatic NK cell subsets (CD49a−) in the liver. These cells exhibit heightened cytokine polyfunctionality with restrained cytotoxic responses upon mitogen stimulation in comparison with CD49a− NK cell ...
Andrew Hudson, Melissa Xin Yu Wong, Michael Verdolin, R Keith Reeves, Cordelia Manickam   +4 more
wiley   +1 more source

The Sanctuary Within: Development of CD20+ CNS Lymphoma Despite Peripheral B-Cell Depletion by Rituximab in a Multiple Sclerosis Patient. [PDF]

Case Rep Neurol Med
Harirchian MH, Mohammadianinejad SE, Bayati A, Soleimani V, Sarvestani Z, Kaeedi M, Havadaragh SH.   +6 more
europepmc   +1 more source

4‐1BB Expression and Signaling Regulates MAIT Cell Activation and Effector Functions

Immunology &Cell Biology, EarlyView.
4‐1BB is a highly expressed TNFRSF co‐stimulatory receptor on MAIT cells upon activation. Expression and signaling via 4‐1BB enhance activation and provide co‐stimulation, boosting MAIT cell effector responses to TCR‐mediated activation. ABSTRACT Mucosal associated invariant T (MAIT) cells are abundant unconventional T cells that recognize microbe ...
Lamichhane R, Williams J, Tirand C, Fouillé R, Wedlock LE, Poudel A, Webley MC, Hannaway RF, Ussher JE   +8 more
wiley   +1 more source

Humoral and Cellular Immune Response in Patients with Hematological Disorders After Three Doses of mRNA COVID-19 Vaccine: A Single-Center Observational Study. [PDF]

Vaccines (Basel)
Daffini R, Zecchini F, Venneri G, Malagola M, Cattaneo C, Calza S, Caruso A, Tucci A, Giagulli C.   +8 more
europepmc   +1 more source

Immune checkpoint inhibitor‐induced eosinophilic fasciitis: A pharmacovigilance and EADV Task force study

Journal of the European Academy of Dermatology and Venereology, EarlyView.
A comprehensive retrospective analysis of 121 immune checkpoint inhibitor‐induced eosinophilic fasciitis cases, including clinical presentation, diagnostic features and treatment outcomes using data from the EADV Task Force ‘Dermatology for Cancer Patients’, two international pharmacovigilance databases and the current literature.
Tristan V. M. Bruijn, Alexandre O. Gérard, Maëlys Labat, Zoe Apalla, Wouter van Binsbergen, Dimitra Koumaki, Valerian Rivet, Frederic Dezoteux, Damien Giacchero, Michael R. Ardern‐Jones, Kara Heelan, Jesse P. Hirner, Ander Mayor, Mariette Labots, Markus V. Starink, Conny J. van der Laken, Vincent Sibaud, Yannick S. Elshot   +17 more
wiley   +1 more source

Impact of Anti-CD20 Therapies on Cytokine, Chemokine and Adhesion Molecule Dynamics in Multiple Sclerosis: A Narrative Review. [PDF]

Neurol Ther
Messner M, Mitterwallner JM, Unterhofer M, Wipfler P, Harrer A, Moser T.   +5 more
europepmc   +1 more source

The Prognostic Significance of Tertiary Lymphoid Structures in Head and Neck Cancers: A Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC), particularly oral squamous cell carcinoma (OSCC), is associated with poor survival despite therapeutic advances. Tertiary lymphoid structures (TLSs) are emerging components of the tumor microenvironment, but their prognostic significance in HNSCC remains unclear.
Everton Freitas de Morais, Bruno Cesar da Costa, Antti Mäkitie, Ricardo D. Coletta, Alhadi Almangush   +4 more
wiley   +1 more source