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FMC7 is an epitope of CD20

Blood, 2008
To the editor: The FMC7 antibody, originally described in 1981,[1][1] detects an antigen expressed on mature human B cells and is used in immunophenotypic analysis and differential diagnosis of lymphomas and leukemias. The identity of the FMC7 antigen was unclear for many years.
Julie P, Deans, Maria J, Polyak
openaire   +2 more sources

Inhibitory FcγRIIb and CD20 internalization

Blood, 2014
In this issue of Blood, Vaughan et al demonstrate that certain antibodies that are used therapeutically in lymphoma treatment (e.g., rituximab) undergo Fcg receptor IIb (FcgRIIb)–mediated internalization from the B-cell surface in a manner that is independent of activation of FcgRIIb with important implications for the design of antibody-based ...
openaire   +2 more sources

P138 Modulation of CD20 expression on B cells by anti-CD20 antibodies

Human Immunology, 2016
Abstract The purpose of this communication is to describe a case that illustrates the interference of in vivo anti-CD20 treatment on B cell crossmatch (B-XM) results. A first kidney transplant candidate, female, white, 31 years-old, with systemic lupus erythematosus, without previous pregnancies, with one blood transfusion more than 15 years ago ...
Elaine C. Bellintani   +6 more
openaire   +1 more source

CD20 as a gatekeeper of the resting state of human B cells

Proceedings of the National Academy of Sciences of the United States of America, 2021
Michael Reth   +2 more
exaly  

CD20+ T cells: an emerging T cell subset in human pathology

Inflammation Research, 2022
Adrian Y. S. Lee
exaly  

Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity

Proceedings of the National Academy of Sciences of the United States of America, 2023
Fredrik Piehl   +2 more
exaly  

Spotlight on anti-CD20.

International MS journal, 2008
Immune modulators, such as interferon beta and glatiramer acetate, have focused on T-cells as the primary therapeutic target, although both drugs affect other cell types as well. There has been a renewed interest in the potential roles of both antibody-dependent and antibody-independent B-cell responses in multiple sclerosis (MS) and its animal model ...
openaire   +1 more source

CD20

1997
A. Neil Barclay   +5 more
openaire   +1 more source

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