Results 131 to 140 of about 5,468 (152)

Nectin-4 reduces T cell effector function and is a therapeutic target in pancreatic cancer. [PDF]

JCI Insight
Heiduk M, Beer C, Cronjaeger S, Kawaler EA, Sommer U, Baenke F, Digomann D, Bufe LN, Reiche C, Glück J, Hoffmann F, Kim S, Stange DE, Simeone DM, Weitz J, Seifert L, Seifert AM.   +16 more
europepmc   +1 more source

Post-Translational Regulation of CD8⁺ T Cell Fate and Dysfunction in Tumor Immunity. [PDF]

Adv Sci (Weinh)
Zhou Z, Chen X, Li N, Zou M, Lin Y, Lin P, Feng W, Zhao X, Cui L.   +8 more
europepmc   +1 more source

Improved expansion of peripheral blood and iPSC-derived natural killer cells for clinical applications. [PDF]

Cell Rep Methods
Thangaraj JL, Lopez E, Kaufman DS.
europepmc   +1 more source

TIGIT Expression and Its Implications in Non-Small-Cell Lung Cancer Progression and Therapy: A Systematic Review. [PDF]

Int J Mol Sci
Piekarz J, Picheta N, Szklener K, Mańdziuk S.   +3 more
europepmc   +1 more source

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8+ T Cells

Immunity, 2020
The activating receptor CD226 is expressed on lymphocytes, monocytes, and platelets and promotes anti-tumor immunity in pre-clinical models. Here, we examined the role of CD226 in the function of tumor-infiltrating lymphocytes (TILs) and resistance to ...
Sébastien Jacquelin, Frank Vari, Mark J. Smyth   +2 more
exaly   +3 more sources

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

Immunity, 2020
International audienceCD8+ T cells within the tumor microenvironment (TME) are exposed to various signals that ultimately determine functional outcomes. Here, we examined the role of the co-activating receptor CD226 (DNAM-1) in CD8+ T cell function.
Guillaume Gaud, Carrié Constantin nadege, Saoudi Abdelhadi   +2 more
exaly   +2 more sources

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Frontiers in Cell and Developmental Biology, 2020
Joseph S Miller, Song Guo Zheng
exaly  

Recovery of CD226-TIGITFoxP3 and CD226-TIGIT-FoxP3 regulatory T cells contributes to clinical remission from active stage in ulcerative colitis patients

Immunology Letters, 2020
Chengbin Wang, Chen Liu, Yan Long
exaly  

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Frontiers in Immunology, 2020
Martha Campbell-Thompson, Mark A Atkinson, Yi-Guang Chen   +2 more
exaly  

CD226 attenuates Treg suppressive capacity via CTLA-4 and TIGIT during EAE

Immunologic Research, 2020
Ning Wang, Liang Fang, Lihua Chen
exaly