Results 121 to 130 of about 8,868 (210)

Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration [PDF]

, 2018
K
Hoyland, Judith A., Kalamegam, Gauthaman, Khademhosseini, Ali, Matta, Csaba, Memic, Adnan, Mobasheri, Ali, Mobasheri, Reza, Poletti, Fabian L., Pushparaj, Peter N., Richardson, Stephen M.   +9 more
core   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, Volume 12, Issue 48, December 29, 2025.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Cell-based monitoring of cancer [PDF]

, 2015
This thesis aimed to optimize the predictive and prognostic information that can be obtained from Circulating Tumor cells (CTC) and Circulating Endothelial Cells (CEC) in whole blood by improving and standardization of their detection and ...
Kraan, J. (Jaco)
core  

Approaches to Enhance Photodynamic Therapy of Lung Cancer: Potential Application of Nanoparticles

Advanced NanoBiomed Research, Volume 5, Issue 12, December 2025.
Bioactive ligand‐targeted nanocarriers can accommodate functionalization with numerous targeting ligands for effective delivery of photosensitizers (PSs) within targeted photodynamic therapy. Various targeting moieties including peptides, antibodies, carbohydrates, aptamers, proteins, and PS anticancer molecules can be attached to nanomaterials.
Nokuphila Winifred Nompumelelo Simelane, Heidi Abrahamse   +1 more
wiley   +1 more source

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans [PDF]

, 2009
El pdf del artículo es la versión pre-print.-- et al-There are no effective antifibrotic therapies for patients with liver diseases. We performed an experimental and translational study to investigate whether ghrelin, an orexigenic hormone with ...
Montserrat Moreno, Javier F. Chaves, Pau Sancho-Bru, Fernando Ramalho, Leandra N. Ramalho, Maria L. Mansego, Carmen Ivorra, Marlene Dominguez, Laura Conde, Cristina Millán, Montserrat Marí, Jordi Colmenero, Juan J. Lozano, Pedro Jares, Josep Vidal, Xavier Forns, Vicente Arroyo, Juan Caballería, Pere Ginès, Ramón Bataller   +19 more
core   +1 more source

Efferocytosis in Health and Disease

MedComm, Volume 6, Issue 12, December 2025.
Efferocytosis in health and disease. Efferocytosis integrates apoptotic cell recognition, engulfment, digestion, and reprogramming to link cell clearance with tissue repair. Molecular checkpoints balance “eat‐me” signals such as phosphatidylserine against inhibitory “don't‐eat‐me” cues like CD47, while TAM receptors, scavenger receptors, and integrins ...
Chaofu Li, Yukun Yang, Fating Zhou, Qiuyan Jiang, Yingying Jiang, Xuanjie Huang, Yiqiong Zhang, Zhengmeng Ye, Gang Xu, Guoying Kao, Ke Zhou, Fan Yang, Jun Xiao, Wei Wu, Chuanwei Li   +14 more
wiley   +1 more source

A risk assessment model of acute liver allograft rejection by genetic polymorphism of CD276

Molecular Genetics & Genomic Medicine, 2019
Background Liver transplantation is an effective therapy for end‐stage liver diseases and acute liver failure. After the operation, however, recipients may suffer grafts loss induced by alloimmune reaction, which is termed as acute allograft rejection ...
Xiaobo Yu, Bajin Wei, Rong Su, Jia Yao, Xiaowen Feng, Guoping Jiang, Haiyang Xie, Jian Wu, Xiao Xu, Min Zhang, Shusen Zheng, Lin Zhou   +11 more
doaj   +1 more source

Are microglial cells the regulators of lymphocyte responses in the CNS? [PDF]

, 2015
The infiltration of immune cells in the central nervous system is a common hallmark in different neuroinflammatory conditions. Accumulating evidence indicates that resident glial cells can establish a cross-talk with infiltrated immune cells, including T-
Almolda Ardid, Beatriz, Castellano López, Bernardo, González, Berta   +2 more
core   +4 more sources

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells [PDF]

, 2013
The transcription factor BATF is required for interleukin 17 (IL-17)-producing helper T cell (TH17) and follicular helper T cell (TFH) differentiation. Here, we show that BATF also has a fundamental role in regulating effector CD8+ T cell differentiation.
Barnitz, R. Anthony, Dilorio, Michael A., Godec, Jernej, Haining, W. Nicholas, Klatt, Martin G., Kurachi, Makoto, Lemieux, Madeleine E., Odorizzi, Pamela M., Regev, Aviv, Wherry, E. John, Yates, Kathleen, Yosef, Nir   +11 more
core   +3 more sources

A Pan-Cancer Analysis of the Oncogenic Role of CD276 in Human Tumors. [PDF]

Genes (Basel)
Objectives: B7 homolog 3 protein (B7-H3, also known as CD276) is a member of the B7 family that has been found to be associated with the growth and progression of a variety of tumors, but no pan-cancer evaluations of CD276 have been performed so far.
Liu L, Yao Z, Liu Y, Li Y, Ding Y, Hu J, Liu Z, Shi P, Chen K, Liu Z, Zhang W, Hou Y.   +11 more
europepmc   +2 more sources