Results 131 to 140 of about 8,868 (210)

An Anti-CD276 Antibody–Drug Conjugate Kills Tumor Cells and Vasculature [PDF]

open access: yesCancer Discovery, 2017
Abstract An antibody–drug conjugate linking anti-CD276 to PBD dimers has antitumor and antimetastatic activity.
openaire   +1 more source

B7-H3/CD276 and small-cell lung cancer: What's new?

open access: yesTranslational Oncology
Immunotherapy revolutionized the treatment landscape of several cancers, including small-cell lung cancer (SCLC), with a huge number of practice-changing trials, and becoming a new frontier for their management. The addition of an anti-PD-L1, atezolizumab or durvalumab, to platinum/etoposide regimen became the standard of care for first-line therapy of
Fabrizio FP, Muscarella LA, Rossi A
openaire   +3 more sources

Clinicopathological features and prognostic value of CD276 expression in female reproductive system malignancies: A meta-analysis

open access: yesTaiwanese Journal of Obstetrics & Gynecology
The relationship between CD276 and malignancies of the female reproductive system has previously been controversial. The purpose of this study was to evaluate the predictive value of CD276 expression in clinicopathological features and prognosis of ...
Hang Su   +3 more
doaj   +1 more source

CD276 is a promising biomarker for the prognosis of clear cell renal cell carcinoma

open access: yesKaohsiung Journal of Medical Sciences
This study aimed to investigate the role of cluster of differentiation 276 (CD276) in evaluating the prognosis of clear cell renal carcinoma (ccRCC) and to build a nomogram for predicting ccRCC progression post‐surgery.
Yan‐Hang Yu   +5 more
doaj   +1 more source

Multidisciplinary Management of Patients with Metastatic Colorectal Cancer [PDF]

open access: yes, 2021
Colorectal cancer Colorectal cancer is the third most common malignant tumor worldwide. Globally, more than 600.000 people die from colorectal cancer every year, mainly from metastatic disease.
Gootjes, Elske Christine
core  

Small Extracellular Vesicle piR-hsa-30937 Derived from Pancreatic Neuroendocrine Neoplasms Upregulates CD276 in Macrophages to Promote Immune Evasion

open access: yesCancer immunology research
The authors show that the piRNA piR-hsa-30937 in PNEN cell–derived small extracellular vesicles (sEV) promotes CD276 expression in macrophages to suppress T-cell immunity.
Yuan-Yuan Zhong   +8 more
semanticscholar   +1 more source

B7-H3 Induces Ovarian Cancer Drugs Resistance Through An PI3K/AKT/BCL-2 Signaling Pathway

open access: yesCancer Management and Research, 2019
Li Zhou,1 Yangchun Zhao2 1Department of Gynecology, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, People’s Republic of China; 2Department of Obstetrics and Gynecology, The Second Affiliated ...
Zhou L, Zhao Y
doaj  

Induction of NK cell reactivity against acute myeloid leukemia by Fc-optimized CD276 (B7-H3) antibody

open access: yesBlood Cancer Journal
Acute myeloid leukemia (AML) remains a therapeutic challenge despite recent therapeutic advances. Although monoclonal antibodies (mAbs) engaging natural killer (NK) cells via antibody-dependent cellular cytotoxicity (ADCC) hold promise in cancer therapy,
Sylwia A. Stefańczyk   +9 more
semanticscholar   +1 more source

Additional file 1 of CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models

open access: yes
Additional file 1: Supplementary Table S1. Primers used in this study. Supplementary Table S2. sgRNA sequences used to target CD276 and FGFR4. Supplementary Table S3. List of the CAR plasmids used for the production of CAR T cells. Supplementary Table S4. Statistical analysis of sdAb-FR4-CAR T cells killing capacity. Supplementary Table S5.
Timpanaro, Andrea   +7 more
openaire   +1 more source

UA19/16/5/7 Athletic Media Relations - Football Film/Video/Audio File [PDF]

open access: yes, 2017
Film, video and audio recordings of football games and football related ...
WKU Archives
core   +1 more source

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