Results 201 to 210 of about 8,868 (210)
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CD276 is differentially expressed in glioblastoma.

Glioblastoma is difficult to treat and patients are often provided poor prognosis (1), indicating a requirement for therapeutic target identification and drug development. Differentially expressed genes represent by definition among the most promising targets for the development of novel chemotherapies (2, 3).
openaire   +1 more source

Abstract 6446: Yap1 and CD276/B7-H3: key players in Sex-biased SHH medulloblastoma immune evasion

Cancer Research
The molecular mechanisms driving sex disparities in cancer prevalence, progression, and treatment outcomes represent a crucial yet understudied area with significant implications for cancer therapy. Medulloblastoma (MB), exhibits a pronounced sex bias in
Nourhan Abdelfattah   +11 more
semanticscholar   +1 more source

B7H3 (CD276) regulation of myeloid cell differentiation in pulmonary fibrosis

The Journal of Immunology
Abstract Myeloid-derived suppressor cells (MDSCs) are induced in cancer and fibrosis, while absent in healthy tissues. The expansions of MDSC are correlated with disease severity and lung function deterioration in the latter. B7H3 induced in lung fibrosis causes the recruitment of MDSCs.
openaire   +1 more source

CD276 Immature Glycosylation Drives Colorectal Cancer Aggressiveness and T-cell Mediated Immune Escape

bioRxiv
Janine Soares   +18 more
semanticscholar   +1 more source

CD276 PREDICTS A POOR RESPONSE TO IMMUNE CHECKPOINT BLOCKAGE IN UROTHELIAL CARCINOMA VIA TUMOR MICROENVIRONMENT REMODELING AND TGF-B SIGNALING

Urologic oncology: Seminars and original investigations
Jack Korleski   +3 more
semanticscholar   +1 more source

637 Two targets – two signals: dual bispecific antibody therapy targeting CD276 and FAP by engaging CD3 and CD28 for solid tumor immunotherapy

Regular and Young Investigator Award Abstracts
I. Hagelstein   +8 more
semanticscholar   +1 more source

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