Clinicopathological and Prognostic Characteristics of CD276 (B7-H3) Expression in Adrenocortical Carcinoma [PDF]
Disease Markers, 2020 Background. Adrenocortical carcinoma (ACC) is a rare malignant endocrine tumor with a high tumor recurrence rate and poor postoperative survival. Recent studies suggest that CD276- (B7-H3) targeted therapy represents a promising therapeutic option for solid tumors.
Jiayu Liang +14 more
openaire +2 more sources
Gene Clusters Based on OLIG2 and CD276 Could Distinguish Molecular Profiling in Glioblastoma [PDF]
Journal of Translational Medicine, 2021 Abstract BackgroundThe molecular classification of glioblastoma (GBM) based on transcriptomic analysis could provide precise treatment and prognosis. However, current subtyping (Classic, Mesenchymal, Neural, Proneural) is a time-consuming and cost-intensive process, which hinders its clinical application.
Minjie Fu +7 more
openaire +4 more sources
High expression of cluster of differentiation 276 indicates poor prognosis in glioma
Clinical Medicine Insights: Oncology, 2021 Background: Glioma is the central nervous system tumor with the highest incidence rate and the molecular detection of gliomas has been the focus of research.
Linchen Li +3 more
doaj +1 more source
Improved diagnosis and prognostication of patients with pleural malignant mesothelioma using biomarkers in pleural effusions and peripheral blood samples – a short report [PDF]
, 2017 Purpose: There is a lack of robust and clinically utilizable markers for the diagnosis and prognostication of malignant pleural mesothelioma (MPM).
Aerts, J.G.J.V. (Joachim) +9 more
core +1 more source
Perinatal stem cells revisited: directions and indications at the crossroads between tissue regeneration and repair. [PDF]
, 2013 Perinatal stem cells research attracted great interest worldwide in recent years. Foetus-associated tissues contain various populations of stem cells, most of which are comprised within the category of mesenchymal stem cells (MSCs).
Anzalone, R., LA ROCCA, G.
core +1 more source
Profiling targetable immune checkpoints in osteosarcoma
OncoImmunology, 2018 Osteosarcomas are aggressive bone tumors for which therapeutic advances have not improved over several decades. Unlike most pediatric tumors, the osteosarcoma genome is remarkably unstable, characterized by numerous copy number alterations and ...
Troy A McEachron +4 more
doaj +1 more source
CD276 as a critical independent biomarker and immune checkpoint inhibitor target in epithelioid mesothelioma-TCGA study. [PDF]
J Thorac DisBackground CD276 is an immune checkpoint, and immune checkpoint inhibitors (ICIs) targeting CD276 have been tested against various cancers. However, the precise role of CD276 in mesothelioma subtypes is unknown.
Aoki Y +5 more
europepmc +2 more sources
Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium. [PDF]
, 2019 ObjectivePopulations of Mexican American ancestry are at an increased risk for nonalcoholic fatty liver disease. The objective of this study was to determine whether loci in known and novel genes were associated with variation in aspartate ...
Chen, Yii-Der I +15 more
core +2 more sources
CD276-directed supramolecular nanoplatform with pH-triggered gemcitabine release for potent tumor stromal and vascular suppression. [PDF]
Int J Pharm XLi J +9 more
europepmc +2 more sources
A Dual-Payload Antibody-Drug Conjugate Targeting CD276/B7-H3 Elicits Cytotoxicity and Immune Activation in Triple-Negative Breast Cancer. [PDF]
Cancer ResAn anti-CD276 monoclonal antibody conjugated with both a cytotoxic drug and an immune boosting reagent effectively targets triple-negative breast cancer by inducing tumor cell death and stimulating immune cell infiltration.
Zhou ZZ +7 more
europepmc +2 more sources