Results 31 to 40 of about 92,785 (261)
Frontiers in Immunology, 2022 Chronic kidney failure (KF) provokes the development of immune senescent CD8+ cytotoxic T cells, affecting the occurrence of graft rejection, viral infections, and malignancies after kidney transplantation.
Jonas Leonhard +6 more
doaj +1 more source
Toxins, 2021 Beta toxin (CPB) is a small hemolysin beta pore-forming toxin (β-PFT) produced by Clostridium perfringens type C. It plays a central role in the pathogenesis of necro-hemorrhagic enteritis in young animals and humans via targeting intestinal endothelial ...
Basma Tarek +3 more
doaj +1 more source
CD31: beyond a marker for endothelial cells [PDF]
Cardiovascular Research, 2012 This editorial refers to ‘A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation’ by G. Fornasa et al. , pp. 30–37, this issue. CD31 is a 130 kDa platelet–endothelial cell (EC) adhesion molecule that was initially identified from ECs and platelets1 and later from blood leucocytes.2 Mature CD31 ...
Li, Liu, Guo-Ping, Shi
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Establishment and validation of glioma patient-derived organoid models
GliomaBackground and Aim: Glioma is one of the most prevalent and refractory brain cancers with a high recurrence rate. Current limitations of experimental in vitro models include their inability to remodel the heterogeneity of the parental tumors and their ...
Anqi Wang +5 more
doaj +1 more source
Distribution of CD15+ and CD31+ cells in the oesophageal mucosa of children with eosinophilic oesophagitis across different age and sex groups [PDF]
Scripta MedicaBackground/Aim: Eosinophilic oesophagitis (EoE) is a chronic immune-mediated inflammatory disease of the oesophagus with a multifactorial nature. The prognosis and effectiveness of therapy for EoE largely depend on a detailed study of its pathogenetic ...
Demyashkin Grigory +7 more
doaj +1 more source
Scientific Reports, 2022 Cluster of differentiation 31 (CD31), phalloidin and alpha smooth muscle actin (α-SMA) have been widely applied to label the cerebral blood vessels in the past years.
Jia Wang +9 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
CD31 − but Not CD31 + Cardiac Side Population Cells Exhibit Functional Cardiomyogenic Differentiation [PDF]
Circulation Research, 2005 Heart failure remains a leading cause of morbidity and mortality. The cellular mechanism underlying the development of cardiac dysfunction is a decrease in the number of viable cardiomyocytes. Recent observations have suggested that the adult heart may contain a progenitor cell population.
Otmar, Pfister +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source