Results 101 to 110 of about 220,756 (241)

Assesment of angiogenesis in basal cell carcinoma using CD31 &CD34 markers and relation with tumor invasiveness in histology [PDF]

open access: yes
Background & Objective : Tumor angiogenesis is essential for tumor growth and appears to play an importating role both in invasive growth and metastasis.
صفايی, زهرا   +3 more
core  

Determination of paracrine factors secreted from primary mADSCs and CD34+ and CD34- mADSCshTERT.

open access: yes, 2016
(A) CM secreted from primary mADSCs, CD34+, and CD34- mADSCshTERT was subjected to a mouse cytokine antibody array detecting 21 cytokines in duplicate. Solid lined boxes indicate differentially secreted paracrine factors among primary mADSCs, CD34+, and ...
Jong-Ho Kim (317877)   +7 more
core   +1 more source

Phase II Study of Posttransplant Cyclophosphamide‐Based Graft‐Versus‐Host Disease Prophylaxis After HLA‐Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Posttransplant cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD) improves outcomes in recipients of HLA mismatched unrelated donor (MMUD) allogeneic hematopoietic cell transplantation (allo HCT). Outcomes of MMUD HCT using PTCy in patients requiring reduced intensity or non‐myeloablative conditioning (RIC/NMA) are not well ...
Brian C. Shaffer   +38 more
wiley   +1 more source

The Presence and Percentage of Circulating Nucleated Red Blood Cells Reveal Distinct Characteristics in Adults With Sickle Cell Disease

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco   +7 more
wiley   +1 more source

Effects of Participation in Volunteer Activities on CD34+ Hematopoietic Stem Cells

open access: yes
Aging populations face health challenges, and volunteering may improve health outcomes. This study investigated the relationship between volunteering, CD34+ hematopoietic stem cells, and health indicators in older adults.
Chang, Chuan-Hsin;Chen, Chia-Chi;Chang, Yue-Cune;Hsieh, Cho Chen;Lin, Chai Ching;Lee, Jia-Fu
core   +1 more source

A Pooled CRISPR Screen Reveals Genes Critical for Erythroblast Enucleation

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Terminal erythroid differentiation involves dramatic cellular remodeling that culminates in the expulsion of the nucleus, a process known as enucleation. While enucleation is conserved across mammals and is crucial for the generation of fully functional erythrocytes, the mechanisms governing this process have remained largely unknown, in part ...
Marilou Tetard   +7 more
wiley   +1 more source

High aldehyde dehydrogenase activity at diagnosis predicts relapse in patients with t(8;21) acute myeloid leukemia

open access: yesCancer Medicine, 2019
Acute myeloid leukemia (AML) with t(8;21) is a heterogeneous disease. Although the detection of minimal residual disease (MRD), which is indicated by RUNX1‐RUNX1T1 transcript levels, plays a key role in directing treatment, risk stratification needs to ...
Lu Yang   +11 more
doaj   +1 more source

Circulating hematopoietic progenitors and CD34+ cells predicted successful hematopoietic stem cell harvest in myeloma and lymphoma patients: experiences from a single institution

open access: yes, 2016
Jui-Ting Yu,1,2,* Shao-Bin Cheng,3,* Youngsen Yang,1 Kuang-Hsi Chang,4 Wen-Li Hwang,1 Chieh-Lin Jerry Teng,1,5,6 1Division of Hematology/Medical Oncology, Department of Medicine, Taichung Veterans General Hospital, 2Division of Hematology/Medical ...
Chang KH   +5 more
core  

CD133-enriched CD34(-) (CD33/CD38/CD71)(-) cord blood cells acquire CD34 prior to cell division and hematopoietic activity is exclusively associated with CD34 expression.

open access: yes, 2007
We compared the cell division behavior of CD34(-) and CD34(+) (CD33/CD38/CD71)-negative (Lin(-)) CD133(+) cord blood cells stimulated with the cytokines Flt3-ligand, stem cell factor, and thrombopoietin. Within a 4-day time frame, Lin(-)CD34(-) CD133(+) (
Götze, KS;Schiemann, M;Marz, S;Jacobs, VR;Debus, G;Peschel, C;Oostendorp, RA
core   +1 more source

Comparative analysis of TP53 gene in Tupaia belangeri subspecies (Tupaia belangeri yaoshanensis vs. Tupaia belangeri chinensis) and identification of mutations in spontaneous tumor cases

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao   +4 more
wiley   +1 more source

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