Results 251 to 260 of about 74,406 (290)

CD36 and taste of fat

Current Opinion in Clinical Nutrition and Metabolic Care, 2012
This review explores the recent literature on the role of CD36 in the taste of fat, eating behavior and obesity risk in rodents and humans.During the last decade, evidence was accumulated supporting the existence of a taste of fat responsible for the spontaneous preference for lipid-rich foods.
Patricia, Degrace-Passilly, Philippe, Besnard   +1 more
openaire   +2 more sources

Erythroid involvement in CD36 deficiency

Experimental Hematology, 2001
The CD36 molecule is expressed in platelets, monocytes, erythroblasts, and other different tissues. The two types of platelet CD36 deficiency, types I and II, are associated with the absence and presence of CD36 on monocytes, respectively. To clarify the involvement of the erythroid lineage in CD36 deficiency, we investigated the phenotype and RNA ...
K, Toba, H, Hanawa, K, Watanabe, I, Fuse, M, Masuko, S, Miyajima, M, Takahashi, M, Sakaue, T, Abo, Y, Aizawa   +9 more
openaire   +2 more sources

CD36 as a lipid sensor

Physiology & Behavior, 2011
CD36 is a multifunctional protein homologous to the class B scavenger receptor SR-B1 mainly found in tissues with a sustained lipid metabolism and in several hematopoieic cells. CD36 is thought to be involved in various physiological and pathological processes like angiogenesis, thrombosis, atherogenesis, Alzheimer's disease or malaria.
Martin, Céline, Chevrot, Michaël, Poirier, Hélène, Passilly-Degrace, Patricia, Niot, Isabelle, Besnard, Philippe   +5 more
openaire   +3 more sources

CD36 expression and brain function: does CD36 deficiency impact learning ability?

Prostaglandins & Other Lipid Mediators, 2005
This article first presents an overview of published literature documenting the role of the scavenger receptor CD36 in activation of brain microglia with reference to brain pathologies such as Alzheimer's and malaria. Second, the possibility that CD36 may play a role in brain FA metabolism is discussed.
Nada A, Abumrad, Mohammad, Ajmal, Kostas, Pothakos, John K, Robinson   +3 more
openaire   +2 more sources

CD36 A critical anti angiogenic receptor

Frontiers in Bioscience, 2003
Thrombospondin-1 (TSP-1) is a potent inhibitor of angiogenesis in vivo and of microvascular endothelial cell responses to angiogenic factors in vitro. CD36 is the cellular receptor for TSP-1 on microvascular endothelium and is necessary for its anti-angiogenic activity.
Ronit, Simantov, Roy L, Silverstein
openaire   +2 more sources

CD36 as a biomarker of atherosclerosis

Free Radical Biology and Medicine, 2014
Atherosclerosis is a chronic inflammatory disorder occurs as a result of mononuclear lymphocyte infiltration to the arterial wall accompanied by smooth muscle cell proliferation and damage in the arterial wall caused by extracellular matrix accumulation.
Burak, Yazgan, Seyfettin, Ustunsoy, Betul, Karademir, Nesrin, Kartal-Ozer   +3 more
openaire   +2 more sources

CD36 is a sensor of diacylglycerides

Nature, 2005
Toll-like receptor 2 (TLR2) is required for the recognition of numerous molecular components of bacteria, fungi and protozoa. The breadth of the ligand repertoire seems unusual, even if one considers that TLR2 may form heteromers with TLRs 1 and 6 (ref. 12), and it is likely that additional proteins serve as adapters for TLR2 activation.
Kasper, Hoebe, Philippe, Georgel, Sophie, Rutschmann, Xin, Du, Suzanne, Mudd, Karine, Crozat, Sosathya, Sovath, Louis, Shamel, Thomas, Hartung, Ulrich, Zähringer, Bruce, Beutler   +10 more
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Pathophysiology of Human Genetic CD36 Deficiency

Trends in Cardiovascular Medicine, 2003
CD36, originally identified as glycoprotein IV on platelets, is an 88-kDa integral membrane protein that has multiple ligands and is expressed in the cardiovascular system (ie, blood vessel walls and the heart). Human genetic CD36 deficiency is relatively frequent in Asian and African populations. Investigation into the pathophysiology of this disorder
Ken-ichi, Hirano, Takahiro, Kuwasako, Yumiko, Nakagawa-Toyama, Mohamed, Janabi, Shizuya, Yamashita, Yuji, Matsuzawa   +5 more
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Harnessing CD36 to Rein in Inflammation

Endocrine‚ Metabolic & Immune Disorders-Drug Targets, 2008
Maintaining health requires a dynamic balance between the influence of pro-inflammatory and anti-inflammatory mediators. While inflammation serves an important protective role against infection, unrestrained inflammation is acutely lethal and unresolved inflammation contributes to a broad range of chronic disorders.
M S, Parsons, L, Barrett, C, Little, M D, Grant   +3 more
openaire   +2 more sources

CD36 Goes Line Dancing

Science Signaling, 2011
Single-particle tracking suggests that some of the surface receptor CD36 is confined in elongated linear domains that promote receptor clustering and signaling.
openaire   +1 more source