Results 291 to 300 of about 1,048,882 (334)

Decoding the Cardiac Immune Microenvironment and Fibroblast Crosstalk in Radiotherapy Combined with Immunotherapy‐Induced Cardiac Fibrosis Based on Single‐Cell Transcriptomic Analysis

Advanced Science, EarlyView.
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo, Ying Yu, Zhimin Zeng, Yanxin Chen, Yali Yi, Zhiqin Lu, Fujuan Zeng, Peng Xu, Daya Luo, Leifeng Chen, Anwen Liu   +10 more
wiley   +1 more source

mTOR pathway mediates the endoplasmic reticulum stress -apoptosis of CD4+ T cell through inhibiting autophagy flux in sepsis. [PDF]

Inflamm Res
Lei X, Zhao G, Xie Y, Cui N.
europepmc   +1 more source

An Enzyme‐Like Catalyzed Nanosheets for Redox Stress Oscillation Therapy Against Bacterial Infections

Advanced Science, EarlyView.
Bacterial biofilms form a physicochemical barrier. Their dense network structure and redox homeostasis confer high resistance to antimicrobial treatments and immune‐mediated killing and clearance. In this study, SnSe nanosheets with enzyme‐like properties and piezoelectric catalysis can oscillate to regulate bacterial redox homeostasis and improve the ...
Min Ge, Zhao Guo, Zhiming Zhang, Lanlu Lu, Zesong Ruan, Tingwang Shi, Yunfeng Chen, Ju Huang, Chaoliang Tan, Han Lin   +9 more
wiley   +1 more source

Accuracy and Acceptability of the VISITECT CD4 Advanced Disease Test Compared With the PIMA CD4 Test at the Point of Care as Part of the Advanced HIV Disease Care Package: A Mixed-Methods Study. [PDF]

Open Forum Infect Dis
Gils T, Misra S, Madonsela T, Pita TP, Bosman S, Ayakaka I, Vlieghe E, van Heerden A, Lynen L, Decroo T, Reither K.   +10 more
europepmc   +1 more source

Integrative analysis of T cell subset-specific ICOS expression and tumor HLA class I/II expression in lung adenocarcinoma: implications for their interaction and clinical outcome. [PDF]

Cancer Immunol Immunother
Yamada H, Yamada R, Komohara Y, Pan C, Yoshii D, Yano H, Matsubara E, Shinchi Y, Tsukamoto H, Fujiwara Y, Ikeda K, Suzuki M.   +11 more
europepmc   +1 more source

New Perspective: Bench to Bedside Evidence of the Role of CD8+ T Cells in Alzheimer's Disease. [PDF]

Immun Inflamm Dis
Peng Y, Yao SY, Wu SL, Yang H, Zhang X, Kazuo S, Liu J, Du MQ, Lin LX, Kang XH, Jiang DY.   +10 more
europepmc   +1 more source

The Hidden Pathway: Membrane Vitamin D Receptor Deficiency and T-Cell Senescence in Pediatric Atopic Dermatitis - A Retrospective and Cross-Sectional Investigation. [PDF]

J Asthma Allergy
Zhu X, Gao X, Wang L, Tang J, Luo L, Yu Q, Qiu B, Shu C, He X.   +8 more
europepmc   +1 more source

Correction to "mTOR Modulates the Endoplasmic Reticulum Stress-Induced CD4+ T Cell Apoptosis Mediated by ROS in Septic Immunosuppression". [PDF]

Mediators Inflamm
europepmc   +1 more source