Results 181 to 190 of about 186,664 (282)
Correction: Jaksic Karisik et al. JQ1 Treatment and miR-21 Silencing Activate Apoptosis of CD44+ Oral Cancer Cells. <i>Int. J. Mol. Sci.</i> 2025, <i>26</i>, 1241. [PDF]
Jaksic Karisik M +5 more
europepmc +1 more source
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang +16 more
wiley +1 more source
The protective role of CD44 and microRNA-146a in tendinopathy. [PDF]
Hsu CC +6 more
europepmc +1 more source
Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD) [PDF]
Karl E. Miletti-González +16 more
openaire +1 more source
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng +12 more
wiley +1 more source
Exercise as Precision Medicine: Targeting HER2/CD44-Driven Therapy Resistance in Breast Cancer (A Mini Review). [PDF]
Edalat Haghi FA, Koushkie Jahromi M.
europepmc +1 more source
Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
Dysregulated hyaluronan metabolism drives inflammation and angiogenesis in proliferative diabetic retinopathy. [PDF]
Abu El-Asrar AM +7 more
europepmc +1 more source

