Results 191 to 200 of about 229,337 (378)

CD44 as a Potential Screening Marker for Preliminary Differentiation Between Congenital Dyserythropoietic Anemia Type II and Hereditary Spherocytosis [PDF]

, 2016
Belinda K. Singleton, Momin Ahmed, C. A. Green, H. Heimpel, Marcin Woźniak, Lepakshi Ranjha, F.M. Seeney, Adrian Bomford, Pramod P. Mehta, A. R. Guest, Rosey Mushens, M.‐J. King   +11 more
openalex   +1 more source

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source

The Hyaluronan Receptors CD44 and Rhamm (CD168) Form Complexes with ERK1,2 That Sustain High Basal Motility in Breast Cancer Cells

, 2007
Sara R. Hamilton, Shireen F. Fard, Frouz Frozan Paiwand, Cornelia Tölg, Mandana Veiseh, Chao Wang, James B. McCarthy, Mina J. Bissell, James Koropatnick, Eva A. Turley   +9 more
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Cancer Stem Cell Gene Profile as Predictor of Relapse in High Risk Stage II and Stage III, Radically Resected Colon Cancer Patients [PDF]

, 2013
Bearzi Italo, Bianconi Maristella, Bittoni Alessandro, Cascinu Stefano, Cecchini Luca, Del Prete Michela, Faloppi Luca, Giampieri Riccardo, Guerrieri Mario, Lezoche Giovanni, Loretelli Cristian, Mandolesi Alessandra, Piva Francesco, Scartozzi Mario   +13 more
core   +1 more source

CD44 regulates epigenetic plasticity by mediating iron endocytosis

bioRxiv, 2019
S. Müller, Fabien Sindikubwabo, T. Cañeque, A. Lafon, A. Versini, Bérangère Lombard, D. Loew, Adeline Durand, C. Vallot, S. Baulande, N. Servant, R. Rodriguez   +11 more
semanticscholar   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

CD44+ cells enhance pro-tumor stroma in the spatial landscape of colorectal cancer leading edge [PDF]

Feiyu Tang, Yongwei Zhu, Jia Shen, Bowen Yuan, Xiang He, Yuxi Tian, Liang Weng, Lunquan Sun   +7 more
openalex   +1 more source

CD44 Is Involved in Tumor Angiogenesis; an Activation Antigen on Human Endothelial Cells [PDF]

, 1997
Arjan W. Griffioen, Marieke J. H. Coenen, Cora A. Damen, Sandra M. M. Hellwig, David H.J. van Weering, Wim Vooys, Geert H. Blijham, Gerard Groenewegen   +7 more
openalex   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source