New Bioinformatic Insight into CD44: Classification of Human Variants and Structural Analysis of CD44 Targeting. [PDF]
Gerlicz WA +3 more
europepmc +1 more source
Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu +16 more
wiley +1 more source
Gold-incorporated hyaluronic acid nanoparticles enhance ablative radiotherapy efficacy in lung cancer. [PDF]
Chen JL +8 more
europepmc +1 more source
STING-associated vasculopathy develops independently of IRF3 in mice [PDF]
Ai, Teresa L +11 more
core +1 more source
Hyaluronan 35 prevents endotoxin-mediated dysregulated skeletal muscle proteostasis during ethanol exposure. [PDF]
Welch N +18 more
europepmc +1 more source
Cuproptosis and Immune Microenvironment Interplay in Temporal Lobe Epilepsy: Identification of Key Molecular Signatures and Therapeutic Targets. [PDF]
Li W +5 more
europepmc +1 more source
Protocol for multi-organ isolation of murine leukocytes for flow cytometry. [PDF]
Layug PJ +4 more
europepmc +1 more source
Chondroitin Sulfate-Based Nanoplatforms: Advances and Challenges for Cancer Therapy. [PDF]
Scorzafave L +5 more
europepmc +1 more source

