Results 331 to 340 of about 229,337 (378)

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

open access: yesAngewandte Chemie, EarlyView.
A covalent allosteric inhibitor M029 was discovered for SHP1, a novel target for immunotherapy. M029 binds to a cryptic Cys remote from the active site, exhibits robust target engagement, and blocks tumor progression by stimulating antitumor immune response.
Zihan Qu   +16 more
wiley   +1 more source

Gold-incorporated hyaluronic acid nanoparticles enhance ablative radiotherapy efficacy in lung cancer. [PDF]

open access: yesInt J Pharm X
Chen JL   +8 more
europepmc   +1 more source

STING-associated vasculopathy develops independently of IRF3 in mice [PDF]

open access: yes, 2017
Ai, Teresa L   +11 more
core   +1 more source

Table S2 from HCK promotes high-grade serous ovarian cancer tumorigenesis through CD44 and NOTCH3 signaling

open access: gold
Christen A. Khella   +5 more
openalex   +1 more source

Hyaluronan 35 prevents endotoxin-mediated dysregulated skeletal muscle proteostasis during ethanol exposure. [PDF]

open access: yesAm J Physiol Endocrinol Metab
Welch N   +18 more
europepmc   +1 more source

Protocol for multi-organ isolation of murine leukocytes for flow cytometry. [PDF]

open access: yesSTAR Protoc
Layug PJ   +4 more
europepmc   +1 more source

Chondroitin Sulfate-Based Nanoplatforms: Advances and Challenges for Cancer Therapy. [PDF]

open access: yesMolecules
Scorzafave L   +5 more
europepmc   +1 more source

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