A new perspective on the pathophysiology of kidney diseases: the intracellular complement system- "complosome". [PDF]
Leventoğlu E, Bakkaloğlu SA.
europepmc +1 more source
Clinical and genetic characteristics of patients diagnosed with atypical hemolytic uremic syndrome (aHUS): epidemiological data from the Belgian cohort of the Global aHUS Registry. [PDF]
Massart A +16 more
europepmc +1 more source
Neutralizing monoclonal antibodies improve biodistribution of intravenously administered oncolytic adenovirus in human CD46-transgenic mice. [PDF]
Hemmi M +3 more
europepmc +1 more source
A Case of Hemolytic Uremic Syndrome Due to a Pathogenic Variant in the DGKE Gene. [PDF]
Chelghoum S +4 more
europepmc +1 more source
Genetic basis of immunity in Indian cattle as revealed by comparative analysis of Bos genome. [PDF]
Thambiraja M +7 more
europepmc +1 more source
JUNO-coated beads as a functional assay to capture and characterize fertilization-competent human sperm. [PDF]
Cots-Rodríguez P +8 more
europepmc +1 more source
CD46 in innate and adaptive immunity: an update
Summary CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a ...
Cardone, J., Le Friec, G., Kemper, C.
exaly +5 more sources

