Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
MedComm, Volume 7, Issue 10, October 2026.The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
MedComm, Volume 7, Issue 10, October 2026.Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Targeting the CD47-SIRPα Axis in Atherosclerosis: From Pathogenesis to Therapeutic Implications. [PDF]
J Inflamm ResSun C +5 more
europepmc +1 more source
Precisely Engineering Biomimetic Nanoparticles via Controlled Cell Membrane Coating
Small, Volume 22, Issue 55, 1 October 2026.Precise engineering of cell membrane‐coated nanoparticles (CMNPs) requires coordinated control over particle size, coating integrity, and membrane leaflet orientation. This review integrates key synthesis parameters, assembly strategies, and analytical methods that govern these features, revealing how structural control underpins biomimetic function ...
Jie Lay Lim +4 more
wiley +1 more source
The CD47 signaling axis regulates the formation and vulnerability of atherosclerotic plaques: mechanism analysis and targeting strategies. [PDF]
Front ImmunolBai L, Xu B, Chen Y, Fu D, Wang L, Ma D.
europepmc +1 more source
Proximity Proteomics Maps Candidate Cellular Uptake Pathways for Cell‐Derived Nanovesicles
Small Methods, Volume 10, Issue 19, 7 October 2026.TurboID‐based dual‐sided proteomics compares mechanically generated cell‐derived nanovesicles with naturally secreted small extracellular vesicles. Vesicle proteomes define candidate interaction signatures, while recipient‐cell proximity labelling identifies exposure‐associated proteins.
Eisuke Kanao +8 more
wiley +1 more source
Macrophage phagocytosis checkpoints in DLBCL immunotherapy: an evidence-maturity framework from CD47 to CD200. [PDF]
Front OncolQi S, Deng L, Luo S, Yao Y, Chen T.
europepmc +1 more source
Investigating changes in beta cell function by modulating CD47
Diabetes is a global health burden characterised by β-cell death and loss of function. Islet transplantation is a recognised treatment for patients with Type 1 Diabetes Mellitus (T1DM) and hypoglycaemic unawareness, but broader application is constrained
Kale, Atharva Rajesh Kumar
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Aging Cell, Volume 25, Issue 10, October 2026.Aging transforms the skeletal muscle microenvironment from a balanced, regenerative niche into a maladaptive, degenerative state. This review highlights how disrupted multicellular crosstalk drives chronic inflammation, fibrosis, and neuromuscular dysfunction, ultimately compromising tissue repair and fueling sarcopenia.
Seongwan Kim +2 more
wiley +1 more source
Targeting efferocytosis with carbonized polymer dots from a natural anti-inflammatory drug to alleviate excessive inflammatory responses in the acute phase of myocardial infarction. [PDF]
Mater Today BioYang Y +9 more
europepmc +1 more source