Results 181 to 190 of about 42,056 (305)

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Hypoimmunogenic Derivatives of Induced Pluripotent Stem Cells Evade Immune Rejection in Fully Immunocompetent Allogeneic Recipients [PDF]

, 2020
Davis, M, De, C, Deuse, T, Garcia, V, Gravina, A, Hu, X, Lanier, L, Reichenspurner, H, Schrepfer, S, Tediashvili, G, Thayer, W, Wahl, A, Wang, D   +12 more
core  

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Prognostic importance of CD47 expression on survival of colorectal cancer

BMC Gastroenterology
Background The exact value of cluster of differentiation 47 (CD47), known as the “don’t eat me” signal, in colorectal cancer (CRC) has not been clearly revealed.
Oktay Halit Aktepe, Olcay Kurtulan, Pinar Ezgi Dama, Eda Caliskan Yildirim, Aytac Terzi, Simin Alara Kalyoncu, Elif Atag, Tugba Yavuzsen, Meral Uner, Aziz Karaoglu, Suayib Yalcin   +10 more
doaj   +1 more source

Xenotransplantation at a Crossroads: Breakthroughs, Challenges, and the Path Forward

Organ Medicine, EarlyView.
Xiaoyu Gan, Jizhang Yu, Jie Wu, Junjie Zong   +3 more
wiley   +1 more source

Nanoshell Fabrication Techniques for Probiotic Encapsulation: A Comprehensive Review

eFood, Volume 7, Issue 3, June 2026.
ABSTRACT Probiotics, beneficial microorganisms, confer numerous health benefits when administered. However, their efficacy is hindered by harsh gut conditions, including acidity, bile acids, and enzymatic degradation. To overcome these challenges, encapsulation and nanoshell technology have emerged as a pivotal strategy to enhance probiotic stability ...
Tuba Mustafa, Muhammad Afzaal, Farhan Saeed, Amna Shahbaz, Zainab Hira, Ayesha Adil, Tayyaba Sohail, Faiyaz Ahmed, Maryam Amanullah, Hina Sarwar, Noor Akram, Saad Mansoor, Gebremichael Gebremedhin Hailu   +12 more
wiley   +1 more source

Macrophage Membrane‐Cloaked, ROS‐Triggered Quercetin Nanocarriers Target Ovarian Lesions to Treat Polycystic Ovary Syndrome

Advanced Healthcare Materials, Volume 15, Issue 17, 8 May 2026.
The synthesis process of MM@PCD@QNPs and its potential mechanism for treating PCOS. (A) Assembly steps of MM@PCD@QNPs. (B) Synthesis and decomposition of MM@PCD@QNPs. (C) Potential therapeutic mechanisms of MM@PCD@QNPs for PCOS. PCD, PABP conjugated with DEX polymer; QUR, quercetin; CDI, N, N′‐carbonyldiimidazole; DEX, dextran; PABP, 4‐(hydroxymethyl ...
Wenzhu Li, Yu Guan, Nan Song, Feng Zhang, Zhimin Deng, Tailang Yin, Yanbing Yang, João Conde, Wenyi Jin, Zhinang Yin   +9 more
wiley   +1 more source

Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication

Nature Medicine, 2022
J. Theruvath, M. Menard, Benjamin A. H. Smith, Miles H. Linde, Garry L. Coles, G. N. Dalton, Wei Wu, L. Kiru, A. Delaidelli, E. Sotillo, John L Silberstein, Anna C. Geraghty, A. Banuelos, Molly Radosevich, Shaurya Dhingra, S. Heitzeneder, Aidan M Tousley, John Lattin, P. Xu, Jing Huang, Nicole Nasholm, Andy He, Tracy C. Kuo, Emma Sangalang, J. Pons, Amira A. Barkal, Rachel E. Brewer, Kristopher D. Marjon, J. Vilches-Moure, Payton L. Marshall, Ricardo A. Fernandes, Michelle Monje, J. Cochran, P. Sorensen, H. Daldrup-Link, I. Weissman, J. Sage, R. Majeti, C. Bertozzi, W. Weiss, C. Mackall, R. Majzner   +41 more
semanticscholar   +1 more source