CD24 in Melanoma: Biomarker, Innate Immune Checkpoint and Emerging Therapeutic Target
ABSTRACT Immune checkpoint inhibitors have transformed the treatment of advanced melanoma, yet many patients develop primary or acquired resistance. Although most work has focused on adaptive checkpoints (PD‐1 and CTLA‐4), accumulating evidence implicates innate immune suppression and stem‐like, drug‐resistant melanoma cell states.
Claudia Lasalle +6 more
wiley +1 more source
CMAH-Targeted Knock-In of Inducible Heme Oxygenase-1 and Constitutive CD47 in GGTA1-Knockout Pigs for Xenotransplantation. [PDF]
Lee H +9 more
europepmc +1 more source
Matrifibrocytes Redefine Cardiac Fibrosis: From Terminal Differentiation to Translational Modulation
ABSTRACT Cardiac fibrosis is increasingly recognized as a dynamic program that resolves into a terminal fibroblast fate, the matrifibrocyte, rather than a persistent myofibroblast state. Lineage‐tracing and single‐cell studies reveal that matrifibrocytes arise from activated myofibroblasts during late scar maturation, lose α‐SMA and proliferative ...
Zhentao Zhang, Hua Zhu
wiley +1 more source
The SIRP family: from structural diversity and signaling mechanisms to implications in immune-related disease targeted therapeutics. [PDF]
Jin Y +6 more
europepmc +1 more source
Podophyllotoxin sensitizes triple-negative breast cancer cells to CD47-targeted immunotherapy. [PDF]
Dang J, Song N, Zhou J, Raoof M, Feng M.
europepmc +1 more source
Thrombospondins in the heart: potential functions in cardiac remodeling [PDF]
Mark W. M. Schellings +109 more
core +1 more source
Recent advances in preclinical studies combining hyperthermia therapy with novel immune checkpoint targeting agents. [PDF]
Li N, Yu J, Wang R, Gong G.
europepmc +1 more source
Engineering macrophages for effective and safe targeting of CD47 cancer cells in the tumor microenvironment. [PDF]
Andón FT +4 more
europepmc +1 more source

