Results 71 to 80 of about 98,906 (300)

WT1‐Targeted Oral Bifidobacterium longum Vaccine Enhances Checkpoint Blockade Efficacy in Pancreatic Cancer

Advanced Science, EarlyView.
Oral WT1‐targeted Bifidobacterium longum vaccine promotes WT1‐associated cellular immunity and enhances anti‐PD‐1/anti‐CTLA‐4 efficacy in pancreatic cancer. ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains largely unresponsive to immune checkpoint inhibitors (ICI) due to its profoundly immunosuppressive tumor microenvironment.
Taiki Yamazaki, Aori Minami, Misako Hirota, Mirei Hirano, Ryota Sato, Atsuki Honma, Hideto Ueki, Toshiro Shirakawa   +7 more
wiley   +1 more source

Correlation between Total Lymphocyte Count, Hemoglobin, Hematocrit and CD4 Count in HIV/AIDS Patients [PDF]

Acta Medica Iranica, 2009
Lymphocyte CD4+count, a standard laboratory test for staging of HIV infection, is expensive and unavailable in resource-restricted countries. Total lymphocyte count (TLC) and hemoglobin (Hb) are recommended as simple & inexpensive surrogates.
Seyed Mohammad Alavi, Fatemeh Ahmadi, Majid Farhadi   +2 more
doaj   +1 more source

Analyses of T lymphocyte subset levels and viral loads in human immunodeficiency virus antibody-confirmed positive cases in Suzhou from 2021 to 2024

Shanghai yufang yixue
ObjectiveTo investigate the T lymphocyte subset levels and viral loads in newly human immunodeficiency virus (HIV) antibody-confirmed positive cases in Suzhou (2021‒2024), and to analyze potential influencing factors by integrating their demographic ...
TIAN Runfang, SHEN Qiang, YA Xuerong, DAI Yue, GAO Qian   +4 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Oral manifestations related to CD4 lymphocyte count in HIV-positive patients

Journal of dental research, dental clinics, dental prospects, 2010
Background and aims. The onset of opportunistic infections in HIV-positive patients is generally associated with a low CD4 count. Oral manifestations can be the first clinical sign of the infection and also determine the progression of disease. The purpose of this study was to determine the prevalence of oral soft tissue manifestations and their ...
Davoodi, Poorandokht, Hamian, Mina, Nourbaksh, Reza, Ahmadi Motamayel, Fatemeh, Noorbaksh, Reza   +4 more
openaire   +3 more sources

The rate of CD4 decline as a determinant of progression to AIDS independent of the most recent CD4 count

, 1998
The data of two cohort studies of HIV-infected individuals were used to examine whether the rate of CD4 decline is a determinant of HIV progression, independent of the most recent CD4 count.
Lepri, AC, Phillips, AN, Lee, CA, Pezzotti, P, Rezza, G, Sabin, CA   +5 more
core  

Total and CD4+ T- lymphocyte count correlation in newly diagnosed HIV patients in resource-limited setting [PDF]

, 2014
Few clinical settings in resource-limited countries perform CD4+ T-lymphocyte counts required as a baseline test for antiretroviral therapy.
Fasakin, K.A, Adebara, I.O, Omoniyi, D.P, Ajayi, O.D, Moronkeji, M.B, Ogundare, R.G, Owoseni, I.S, Omisakin, C.T, Esan, A.J   +8 more
core  

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Optimization of an Antiviral Treatment Regimen for Immunological Nonresponders Through HIV-DNA Resistance Testing: A Case Report

Journal of the International Association of Providers of AIDS Care
In August 2012, a 47-year-old male patient was diagnosed with human immunodeficiency virus (HIV) infection, with no other underlying disease or opportunistic infection.
Kun He MS, Xiang Du MS, Qi Cao BM, Mingjun Li MS, Juan Qian BM, Min Liu MS   +5 more
doaj   +1 more source

Lymphocyte subset counts as diagnostic and prognostic markers for carbapenem-resistant Enterobacteriaceae (CRE) infection in critically ill patients

International Journal of Infectious Diseases, 2020
Objectives: This study investigated the use of lymphocyte subset counts as diagnostic and prognostic markers for carbapenem-resistant Enterobacteriaceae (CRE) infection. Methods: We assessed the lymphocyte subset populations and other clinical parameters
Wei Cheng, Hao Wang, Jiahui Zhang, Guangxu Bai, Wen Han, Jianwei Chen, Na Cui   +6 more
doaj   +1 more source