Results 91 to 100 of about 98,906 (300)

Correlation Between Total Lymphocyte Count and CD4 Lymphocyte Count in Children Infected with HIV [PDF]

, 2006
INTRODUCTION: As of the end of 2003, an estimated 42 million people worldwide - 38.6 million adults and 3.2 million children younger than 15 years - were living with HIV/AIDS. Approximately 70 percent of these people (29.4 million) live in Sub-Saharan
Chezhiyan, M
core  

Amplification of Endoplasmic Reticulum Stress via Inhibiting Lipid Droplet Formation to Enhance Chemodynamic Immunotherapy

Advanced Science, EarlyView.
An endoplasmic reticulum (ER)‐targeted chemodynamic nanoagent (TCBQ/iLD‐ER NPs) comprising •OH‐generating tetrachloro‐1,4‐benzoquinone (TCBQ) and lipid droplets (LDs) formation inhibitor (iLD) is developed for chemodynamic immunotherapy of tumors. After ingestion by cancer cells, TCBQ/iLD‐ER NPs preferentially accumulate in the ER and react with ER ...
Huilan Cai, Shaoru Zhuang, Yang Zhu, Rujiang Ao, Meili Yu, Tingting Cui, Jun Wang, Xuegang Niu, Hongwei Huang, Shanshan Peng, Yu He, Lisen Lin, Huanghao Yang   +12 more
wiley   +1 more source

Assessment of HIV disease progression before and after initiation of anti­retroviral therapy by CD4 & CD8 T-lymphocyte count and viral load assay

Bangabandhu Sheikh Mujib Medical University Journal, 2016
Backgrounds: As there is no published data regarding the response to Anti-retroviral therapy (ART) among HIV patients from Bangladesh. The present study was designed to determine the immunological and virological responses of HIV infected Bangladeshi ...
Sahina Tabassum, S.M. Rashed-ul Islam, Afzalun Nessa, Munira Jahan, Saif Ullah Munshi   +4 more
doaj   +1 more source

Immunogenetics of CD4 lymphocyte count recovery during antiretroviral therapy: An AIDS clinical trials group study

, 2006
During antiretroviral therapy, CD4 lymphocyte count increases are modest in some patients despite virologic control. We explored whether polymorphisms in genes important for T cell expansion, survival, and apoptosis are associated with the magnitude of ...
Andersen, Janet, Benson, Constance A., Motsinger, Alison A., Landay, Alan, D'Aquila, Richard T., Unutmaz, Derya, Geraghty, Daniel E., Mar, Jessica, Haas, David W., Ritchie, Marylyn D.   +9 more
core   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

CD4 T-lymphocyte cell counts and pneumonia in HIV children

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2018
CD4 T-lymphocyte cell counts and pneumonia in HIV-infected children Abstract Background Pneumonia is a major cause of morbidity and the most common cause of mortality in infants and children who are infected with Human Immunodeficiency Virus (HIV). For
Siti Habsyah Masri
doaj   +3 more sources

HAART \u2013 Dependent CD4+ Lymphocyte Response Based on Pre-Therapeutic CD4 Lymphocyte Count in HIV-Infected Nigerians [PDF]

, 2006
Background: Increasing concerns related to cost, drug toxicity, pill burden, tolerability ability of patient to adhere to strict and complicated regimen and emergence of drug resistance has complicated the decision making process of when to start ...
Uko, E. K., Erhabor, O., Ejele, O. A.
core  

Total lymphocyte count as surrogate marker for CD4 cell count in HIV-infected individuals in Gondar University Hospital, Northwest Ethiopia [PDF]

, 2012
Background: The high cost of CD4 count estimation in resource-limited countries is a major challenge in initiating patients on highly active antiretroviral therapy (HAART).
Yitayih Wondimeneh, Dagnachew Muluye, Yismaw, Gizachew, Gizachew Yismaw, Getachew Ferede, Wondimeneh, Yitayih, Ferede, Getachew, Muluye, Dagnachew   +7 more
core   +1 more source

PANX2 Suppresses Lung Adenocarcinoma Progression by Inducing Disulfidptosis and Enhancing Antitumor Immunity

Advanced Science, EarlyView.
ABSTRACT Lung adenocarcinoma (LUAD) remains a leading cause of cancer mortality with limited therapeutic options. Disulfidptosis, a novel cell death modality driven by disulfide stress, represents a promising target, yet its regulation in LUAD is poorly defined. Here, we identify Pannexin 2 (PANX2) as a tumor suppressor in LUAD.
Yi Chen, Zhao‐Yu Liu, Gao‐Wen Qu, Run‐Hao Zeng, Wen‐Xia Yao, Yong‐Bing Zhou, Xue Liang, Yu‐Xiong Lai   +7 more
wiley   +1 more source

Local reference ranges for full blood count and CD4 lymphocyte count testing.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2009
Recent advances in full blood count and CD4 technology, coupled with the changing population demographics of the Gauteng region, have necessitated reevaluation of the reference ranges currently in use.A cross-sectional study of 631 female and 88 male HIV-negative participants from the Gauteng region was performed.
Lawrie, Denise, Coetzee, Lindi Marie, Becker, Piet, Mahlangu, Johnny, Stevens, Wendy, Glencross, Deborah Kim   +5 more
openaire   +3 more sources