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Polymorphism of chicken CD8-alpha, but not CD8-beta
Immunogenetics, 1997We report here the structural basis of CD8 polymorphism in the chicken. Three chicken strains (RPRL Line 7, H.B15.H7, and H.B15. H12) have 14 nucleotide differences in the CD8A cDNA sequence causing eight amino acid replacements in the extracellular part of the molecule.
M, Luhtala +3 more
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2004
Publisher Summary The term “effector cell” best describes differentiated T cells with immediate TcR-triggered cytotoxicity or cytokine secretion, as detected in short-term assays, which are currently only feasible in vitro. Investigators agree that antigen recognition by naive CD8+ T cells does not result in either type of effector function (the IL-2
Pierre A, Henkart, Marta, Catalfamo
openaire +2 more sources
Publisher Summary The term “effector cell” best describes differentiated T cells with immediate TcR-triggered cytotoxicity or cytokine secretion, as detected in short-term assays, which are currently only feasible in vitro. Investigators agree that antigen recognition by naive CD8+ T cells does not result in either type of effector function (the IL-2
Pierre A, Henkart, Marta, Catalfamo
openaire +2 more sources
Seminars in Immunology, 2004
This review describes what is generally known about CD8 immune responses, and focus in the most recent advances in this domain. It also attempts to point to the areas where experimental evidence is contradictory or insufficient, and thus require further exploration and clarification.
B, Rocha, C, Tanchot
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This review describes what is generally known about CD8 immune responses, and focus in the most recent advances in this domain. It also attempts to point to the areas where experimental evidence is contradictory or insufficient, and thus require further exploration and clarification.
B, Rocha, C, Tanchot
openaire +2 more sources
Anti-CD8 conjugated nanoparticles to target mammalian cells expressing CD8
International Journal of Pharmaceutics, 2010This work aimed at the development of targeted drug delivery systems using nanoparticles fused with antibodies. The antibody anti-human CD8 was coupled onto PLGA nanoparticles, and the ability of these particles to specifically target cells expressing CD8 was studied.
A, Bicho +3 more
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AIDS Research and Human Retroviruses, 1999
The distribution and function of lymphocytes vary in different clinical states. The object of this study was to characterize the CD8+ lymphocyte subpopulations and CD8+ anti-HIV suppressor activity in HIV-infected and uninfected pregnant and nonpregnant women.
K C, Rich +4 more
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The distribution and function of lymphocytes vary in different clinical states. The object of this study was to characterize the CD8+ lymphocyte subpopulations and CD8+ anti-HIV suppressor activity in HIV-infected and uninfected pregnant and nonpregnant women.
K C, Rich +4 more
openaire +2 more sources
Nature Reviews Immunology, 2019
A mix of 11 strains of commensal bacteria is shown to specifically induce potent antimicrobial and antitumour IFNγ-producing CD8+ T cells in mice.
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A mix of 11 strains of commensal bacteria is shown to specifically induce potent antimicrobial and antitumour IFNγ-producing CD8+ T cells in mice.
openaire +2 more sources