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Seminars in Immunopathology, 2019
CD8+ T cells are important for the protective immunity against intracellular pathogens and tumor. In the case of chronic infection or cancer, CD8+ T cells are exposed to persistent antigen and/or inflammatory signals. This excessive amount of signals often leads CD8+ T cells to gradual deterioration of T cell function, a state called "exhaustion ...
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CD8+ T cells are important for the protective immunity against intracellular pathogens and tumor. In the case of chronic infection or cancer, CD8+ T cells are exposed to persistent antigen and/or inflammatory signals. This excessive amount of signals often leads CD8+ T cells to gradual deterioration of T cell function, a state called "exhaustion ...
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2015
??????????????????????, ???? CD4+ ?? CD8+ ??-?????????????????? ?????????????????????????? ?? ???????????? ?????????????????? ?????????????? ?? ???????????????? ???????????????????????? ?????????????????? ?????????????????? ?????? ????????????????????????????????????. ?????????????????????? ?? ?????????????????????? ?????????????????????????? CD8+ ??-??
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??????????????????????, ???? CD4+ ?? CD8+ ??-?????????????????? ?????????????????????????? ?? ???????????? ?????????????????? ?????????????? ?? ???????????????? ???????????????????????? ?????????????????? ?????????????????? ?????? ????????????????????????????????????. ?????????????????????? ?? ?????????????????????? ?????????????????????????? CD8+ ??-??
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