Results 271 to 280 of about 419,552 (297)

SPP1+ Tumor-Associated Macrophages Drive Immunotherapy Resistance via CD8+ T-cell Dysfunction in Clear-Cell Renal Cell Carcinoma. [PDF]

open access: yesCancer Immunol Res
Jiang W   +9 more
europepmc   +1 more source

Comparative profiling of T cell and macrophage subsets in cutaneous squamous cell carcinoma and basal cell carcinoma. [PDF]

open access: yesSci Rep
Winter L   +8 more
europepmc   +1 more source

Co-expression of PD1+ and HLA-DR+ in CD8+ T cells is increased in tonsils of children with EBV primary and persistent infection. [PDF]

open access: yesFront Immunol
Amarillo ME   +10 more
europepmc   +1 more source

Polymorphism of chicken CD8-alpha, but not CD8-beta [PDF]

open access: possibleImmunogenetics, 1997
We report here the structural basis of CD8 polymorphism in the chicken. Three chicken strains (RPRL Line 7, H.B15.H7, and H.B15. H12) have 14 nucleotide differences in the CD8A cDNA sequence causing eight amino acid replacements in the extracellular part of the molecule.
John R. Young   +3 more
openaire   +2 more sources

CD8+ T cells in autoimmunity [PDF]

open access: possibleCurrent Opinion in Immunology, 2005
Mounting evidence shows that CD8(+) T cells contribute to the initiation, progression and regulation of several pathogenic autoimmune responses in which these cells were not previously thought to play a major role. CD8(+) T cells can kill target cells directly, by recognizing peptide-MHC complexes on target cells, or indirectly, by secreting cytokines ...
Pere Santamaria, Ulrich Walter
openaire   +2 more sources

Antimetastatic defense by CD8+ T cells

Trends in Cancer, 2022
Metastasis is an intricate process whereby tumor cells migrate from the primary tumor, survive in the circulation, seed distal organs, and proliferate to create metastatic foci. CD8+ T cells can detect and eliminate tumor cells. Research on CD8+ T cell-dependent antitumor immunity has classically focused on its role in the primary tumor.
Paulino Tallón de Lara   +5 more
openaire   +3 more sources

CD8 T cell memory

Seminars in Immunology, 2004
This review describes what is generally known about CD8 immune responses, and focus in the most recent advances in this domain. It also attempts to point to the areas where experimental evidence is contradictory or insufficient, and thus require further exploration and clarification.
B. Rocha, C. Tanchot
openaire   +2 more sources

CD8 T Cells and Aging

Critical Reviews in Immunology, 2003
Aging of the immune system, or "immunosenescence," is associated with both a marked reduction in responsiveness as well as functional dysregulation. These changes have been implicated in the increased morbidity and mortality of the elderly population from infectious disease, and may also play a role in autoimmunity and cancer.
Zeling Cai   +2 more
openaire   +2 more sources

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