Results 251 to 260 of about 459,921 (305)

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Hybrid Insulin Peptides as Antigens and Tolerogens for Pathogenic T Cells in Autoimmune Diabetes. [PDF]

Immunol Rev
Haskins K, Delong T, DiLisio JE, Baker RL.   +3 more
europepmc   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

Thymic APC Networks Orchestrate T-Cell Selection: Mechanisms and Therapeutic Opportunities in Immune Disorders. [PDF]

Immunology
Luo Y, Wang W, Yan J.
europepmc   +1 more source

Virome antigens as triggers for immune recognition of mutant clones in normal tissues. [PDF]

JCI Insight
Andresen NE, Son HG, Joh JJ, Demehri S.
europepmc   +1 more source

A distinct antigen presentation pathway drives potent T cell immunity in lipid nanoparticle-based mRNA vaccines. [PDF]

Sci Adv
Muro R, Wang S, Ito-Kureha T, Huynh HH, Kobiyama K, Sugita T, Okamoto K, Nakano K, Okamura T, Kubo M, Ishii KJ, Nitta T, Takayanagi H.   +12 more
europepmc   +1 more source

mRNA-based tuberculosis vaccines BNT164a1 and BNT164b1 are immunogenic, well tolerated and efficacious in rodent models. [PDF]

Nat Immunol
Agrawal N, Ates LS, Schille SA, Chaturvedi A, Vogt J, Vukovic N, Dulberger CL, Vogel AB, Diekmann J, Diken M, Şahin U.   +10 more
europepmc   +1 more source

Repeated Immunization Drives Coordinated Ag Presentation Associated With B- and CD8⁺ T-Cell Responses in Liver-Stage Malaria. [PDF]

Immune Netw
Tandel N, Tyagi RK.
europepmc   +1 more source

A multitargeting nanoparticle-based vaccine for enhanced anticancer immunotherapy in HER2-Positive breast cancer. [PDF]

Mater Today Bio
Liu S, Zhu Y, Chen T, Liu X, Lai J, Hu M, Liu Y, Rao H, Zhang B, Xiao S, Peng H, Liang T, Xie L, Qiu G, Li S, Ma X.   +15 more
europepmc   +1 more source

Decoding HBV-specific adaptive immunity: from natural clearance to cure. [PDF]

Gut
Thimme R, Hofmann M, Bertoletti A, Le Bert N.   +3 more
europepmc   +1 more source