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The Expansion and Maintenance of Antigen‐Selected CD8+ T Cell Clones
2007The biological purpose of the mature, postthymic CD8(+) T cell is to respond to microbial antigens with a developmental program of clonal expansion and concomitant differentiation leading to effector cells (T(EFF)) that provide antimicrobial defense. Because many microbial infections persist into a chronic phase, this antigen-stimulated developmental ...
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Cancer germline antigens and tumor-agnostic CD8+ T cell evasion
Trends in Immunology, 2022Dian Kortleve +2 more
exaly
B-chronic lymphocytic leukemia with aberrant expression of CD8 antigen
2001SUMMARY - OBJECTIVE: The aim of this study was to describe an unusual phenotype in otherwise typical B-chronic lymphocytic leukemia (B-CLL) and confirm its belonging to the neoplastic cell clone. PATIENTS AND METHODS: Peripheral blood (PB) samples of 140 patients (91F/49 M, median age 61.0 years) with B-CLL were analysed by flow
Kardum, Mirjana-Marijana +5 more
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Human CD3+ T lymphocytes that express neither CD4 nor CD8 antigens.
Journal of Experimental Medicine, 1986Lewis L Lanier, Lanier L L, Phillips J H
exaly

