Results 161 to 170 of about 24,240 (208)
Tissue-Specific Expansion of Age-Associated B Cells via IFN-γ and IL-21 Within Salivary Glands in Sjögren Disease. [PDF]
J Immunol ResNishida M +7 more
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RNA binding protein Sam68 promotes germinal center reaction and IgG response through regulation of miR29. [PDF]
Cell Mol Life SciDatta M +4 more
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CD95 tyrosine phosphorylation is required for CD95 oligomerization
Apoptosis: an International Journal on Programmed Cell Death, 2006Proapoptotic stimuli, such as CD95 ligand and hydrophobic bile acids induce an epidermal growth factor receptor (EGFR)-catalyzed tyrosine phosphorylation of CD95-death receptor in hepatocytes, as a prerequisite for CD95-translocation to the plasma membrane, formation of the death-inducing signalling complex and execution of apoptotic cell death ...
Dieter Häussinger +2 more
exaly +3 more sources
Cytotoxic drugs and the CD95 pathway [PDF]
Leukemia, 1999 Cytotoxic drugs commonly used in chemotherapy of leukemia and solid tumors have been shown to primarily act by inducing apoptosis in sensitive target cells. Apoptosis may involve activation of death-inducing ligand/receptor systems such as CD95 (APO-1/Fas).
Simone Fulda +2 more
exaly +3 more sources
2011
Summary. CD95 expression on peripheral blood lymphocytes of 72 patients with chronic lymphocytic leukaemia (CLL) depending on the stage of disease, cytopenia pattern and the treatment schedules. A low (0???5%) level of CD95+ cells was detected in the majority (78%) of patients.
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Summary. CD95 expression on peripheral blood lymphocytes of 72 patients with chronic lymphocytic leukaemia (CLL) depending on the stage of disease, cytopenia pattern and the treatment schedules. A low (0???5%) level of CD95+ cells was detected in the majority (78%) of patients.
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CD95 is not functional in human erythrocytes
International Journal of Laboratory Hematology, 2010SummaryIntroduction: The CD95 pathway is a potent inducer of apoptosis in nucleated cells and this death receptor is important for proper blood cell development. Although it is expressed in red blood cells, its functional role in erythrocytes is not well documented.
D, Sagan +2 more
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The CD95 system and the death of a lymphocyte
Seminars in Immunology, 1997Since the discovery of the CD95 receptor in 1989 and its ligand in 1993 as major initiators of apoptosis, extensive progress has been made in understanding their functions in programmed cell death. This review will summarize the cellular, molecular and biochemical requirements that play an important role in the CD95 system.
Sara M Mariani, S M Mariani, P H Krammer
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CD95 Signaling in Cancer Treatment
Current Pharmaceutical Design, 2014The CD95/CD95 ligand (CD95L) system regulates cell death, which plays a relevant role in cancer. The impairment of the CD95/CD95L system in cancer cells may lead to apoptosis resistance and contributes to tumor progression. However, a complete loss of CD95 is rarely seen in human cancers, and many cancer cells express large quantities of CD95 ...
Angel J, De la Rosa +4 more
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