Results 211 to 220 of about 1,680,486 (323)

Mass spectrometry-based discovery and diagnostic validation of T. cruzi antigens in the urine of congenitally infected Chagas Disease patients. [PDF]

PLoS Negl Trop Dis
Cassels K, Almofeez R, Roman J, Steinberg H, Byne A, Haymond A, Tinajeros F, Del Carmen Menduiña M, Málaga Machaca E, Verástegui M, Ramírez JL, Liotta L, Gilman RH, Luchini A.   +13 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Main genetic factors associated with inflammatory bowel diseases and their consequences on intestinal permeability: involvement in gut inflammation. [PDF]

J Gastroenterol
Mauduit A, Mas E, Solà-Tapias N, Ménard S, Barreau F.   +4 more
europepmc   +1 more source

Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead‐cell‐associated antigens partially through a ceramide‐dependent pathway to enhance CD4⁺ T‐cell responses [PDF]

, 2016
Yingping Xu, Yi Liu, Chunqing Yang, Li Kang, Mei‐Xiang Wang, Jingxia Hu, Hao He, Wengang Song, Hua Tang   +8 more
openalex   +1 more source

Chronic ER Stress Triggers Cell‐Surface Chaperones as the Therapeutic Targets of CAR Cells in Acute Myeloid Leukemia

Advanced Science, EarlyView.
Acute myeloid leukemia (AML) remains a therapeutic challenge due to its heterogeneity and limited targets. Here, multi‐omics analyses are utilized, and it is revealed that AML cells, particularly the FLT3‐ITD+ subtype, undergo chaperone‐mediated ER stress, inducing surface translocation of ER chaperones.
Yimin Zhou, Zhenfei Zhong, Peng Hu, Weigang Wang, Ying Song, Na Yang, Fangyan He, Yajie Li, Qi Sa, Yanmei Yang, Qinmiao Sun, Tonghua Yang, Beibei Zhang, Dahua Chen   +13 more
wiley   +1 more source

Diagnostic Performance of Chimeric Recombinant Antigens of Trypanosoma cruzi for Identifying Chagas Disease in Samples From Rio Grande do Sul. [PDF]

Trop Med Int Health
Silva ÂAO, de Leon ÍF, de Jesus FSS, Sampaio DD, Voigt ALB, Pinheiro NB, Bottari NB, Castaño-Barrios LM, Celedon PAF, Zanchin NIT, Marchini FK, Berne MEA, Santos FLN.   +12 more
europepmc   +1 more source

CD19‐Chimeric Antigen Receptor T Cells for Treatment of Chronic Lymphocytic Leukaemia and Acute Lymphoblastic Leukaemia [PDF]

, 2015
Cathrine Lund Lorentzen, Per thor Straten   +1 more
openalex   +1 more source

Chronic PET‐Microplastic Exposure: Disruption of Gut–Liver Homeostasis and Risk of Hepatic Steatosis

Advanced Science, EarlyView.
Chronic exposure to environmentally relevant PET microplastics disrupts gut–liver homeostasis, leading to hepatic steatosis, early fibrosis, and altered gut microbiota. These effects signal metabolic imbalance and gut–liver axis impairment, emphasizing chronic microplastic ingestion as an emerging environmental health risk linked to non‐communicable ...
Surye Park, Min‐Ji Kim, Jae‐Ho Shin, Eunsoo Kim, Myeongjoo Son, Seungjun Lee   +5 more
wiley   +1 more source

IgG4 unveiled: navigating the interplay with Crohn's disease - from immunology insights to machine learning. [PDF]

Ann Med Surg (Lond)
Mohan A, Ghaffar U, Basharat A, Nawaz G, Khenhrani RR, Rimsha, Vera GJA, Lal PM, Tanush D, Khan MK, Duseja N, Sherazi SL, Vikash, Kumar V, Nanavaty D.   +14 more
europepmc   +1 more source

Conformational study of a short Pertussis toxin T cell epitope incorporated in a multiple antigen peptide template by CD and two‐dimensional NMR [PDF]

, 1993
Gennaro Esposito, Federico Fogolari, Paolo Viglino, Serge Cattarinussi, Maria Teresa De Magistris, Lorella Chiappinelli, Antonello Pessi   +6 more
openalex   +1 more source