Results 51 to 60 of about 301,711 (248)

Mechanistic investigation of the associations between bacterial community composition and cadmium distribution in Zizania latifolia

open access: yesEcotoxicology and Environmental Safety
The role of bacteria in external niches regulating cadmium (Cd(II)) in plant tissues remains unclear. We explored Cd(II) profiles and identified bacterial contributors among phyllosphere, rhizoplane, and rhizosphere of four Zizania latifolia varieties ...
Chen-Xi Fu   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

OPTIMALISASI TRANSPORT SELEKTIF ION Ni(II) TERHADAP Cd(II) DENGAN ZAT PEMBAWA OKSIN MELALUI TEKNIK MEMBRAN CAIR FASA RUAH SECARA SIMULTAN

open access: yesJurnal Riset Kimia, 2015
The selective transport of Ni(II) to Cd(II) through simultaneously liquid membrane technique has been investigated. The cell membrane was made by mixturing Ni(II) and Cd(II) ions at concentration as 3.41x10-4 M and 1.78x10-4 M respectively as source ...
Vera Tri Ningsih   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Polarographic Determination of Antihistamines by Complexation with Cd(II)

open access: yesJournal of AOAC INTERNATIONAL, 1986
Abstract The polarographic behavior of the complexes formed by Cd(II) ion with ethanolamine derivative antihistamines such as diphenhydramine hydrochloride, dimenhydrinate, and chlorphenoxamine hydrochloride was studied. Antihistamines form spontaneous complexes with Cd(II) ion in the presence of KNO3.
A, Temizer, N, Ozaltin
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Remediation of Cd(II) contamination in aqueous solution by modified sludge biochar with molten salt-assisted pyrolysis

open access: yesDesalination and Water Treatment
In this work, modified sludge biochar was prepared using molten salt-assisted pyrolysis method to remove Cd(II) from aqueous solution. The biochar was characterized using XRD, FTIR, Raman, XPS and pore structure analysis techniques, and the effects of ...
Yanxin Yao
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

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