Results 181 to 190 of about 9,622 (224)
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Molecular and Cellular Endocrinology, 2002
To obtain selective antiprogestins, we have examined the in vitro antiprogestational/antiglucocorticoid properties of two novel compounds, CDB-4124 and the putative monodemethylated metabolite, CDB-4453, in transcription and receptor binding assays and compared them to CDB-2914 and mifepristone.
Jerry R Reel
exaly +3 more sources
To obtain selective antiprogestins, we have examined the in vitro antiprogestational/antiglucocorticoid properties of two novel compounds, CDB-4124 and the putative monodemethylated metabolite, CDB-4453, in transcription and receptor binding assays and compared them to CDB-2914 and mifepristone.
Jerry R Reel
exaly +3 more sources
CDB-4124 Does Not Cause Apoptosis in Cultured Fibroid Cells
Reproductive Sciences, 2011 Selective progesterone receptor modulators (SPRMs), such as asoprisnil (J867) and ulipristal (CDB-2914), have been shown to reduce fibroid volume in vivo and to induce apoptosis in vitro. CDB-4124 (telapristone), a SPRM with different side groups, also reduced fibroid volume in vivo, and we hypothesized that this SPRM would also cause apoptosis in ...
Hilary, Roeder +3 more
core +5 more sources
Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells. [PDF]
Molecular Human Reproduction, 2008 Effects of progesterone receptor modulator CDB-2914 on the expression of the extracellular matrix (ECM) components were examined in cultured human uterine leiomyoma and myometrial cells. ECM metalloproteinase inducer (EMMPRIN), matrix metalloproteinases (
Shigeki Yoshida, Noriyuki Ohara, T Maruo
exaly +2 more sources
Human Reproduction, 2006 Background: This study was conducted to evaluate the effects of graded concentrations (10-8, 10-7 and 10-6 M) of progesterone receptor (PR) modulator CDB-2914 on the protein contents of PR, of vascular endothelial growth factor (VEGF), adrenomedullin ...
Noriyuki Ohara
exaly +2 more sources
Proceedings of the VLDB Endowment, 2018
Crowd-powered database systems can leverage the crowd's ability to address machine-hard problems, e.g., data integration. Existing crowdsourcing systems adopt the traditional tree model to select a good query plan. However, the tree model can optimize the I/O cost but cannot optimize the monetary cost, latency and quality, which are three important ...
Guoliang Li 0001 +9 more
openaire +1 more source
Crowd-powered database systems can leverage the crowd's ability to address machine-hard problems, e.g., data integration. Existing crowdsourcing systems adopt the traditional tree model to select a good query plan. However, the tree model can optimize the I/O cost but cannot optimize the monetary cost, latency and quality, which are three important ...
Guoliang Li 0001 +9 more
openaire +1 more source
Proceedings of the 2017 ACM International Conference on Management of Data, 2017
Crowdsourcing database systems have been proposed to leverage crowd-powered operations to encapsulate the complexities of interacting with the crowd. Existing systems suffer from two major limitations. Firstly, in order to optimize a query, they often adopt the traditional tree model to select an optimized table-level join order.
Guoliang Li 0001 +9 more
openaire +2 more sources
Crowdsourcing database systems have been proposed to leverage crowd-powered operations to encapsulate the complexities of interacting with the crowd. Existing systems suffer from two major limitations. Firstly, in order to optimize a query, they often adopt the traditional tree model to select an optimized table-level join order.
Guoliang Li 0001 +9 more
openaire +2 more sources
Pharmacologic properties of CDB(VA)-2914
Steroids, 2003CDB(VA)-2914 (17alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione) is a synthetic steroid that demonstrates potent progesterone antagonist activity in vitro and in vivo. Its binding and antagonist potency with respect to the glucocorticoid receptor is significantly reduced compared to that of mifepristone, indicating ...
Erin E, Gainer, André, Ulmann
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The CDB/HCDB semiconductor wafer representation server
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 1993The chip database (CDB) and the hierarchical chip database (HCDB) and their uses in a wafer representation server are described. The server provides data types and methods for hierarchically representing the three-dimensional geometry and fields of a semiconductor wafer during process, device, and yield simulation. The basic database data types and the
D. M. H. Walker +3 more
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CDB-PV: A Constraint Database-Based Program Verifier
2007In this paper we present a new system called CDB-PV that uses constraint databases (CDBs) for program verification (PV). The CDB-PV system was implemented in C++ and tested on several sample programs that are difficult to verify using other methods. The CDB-PV system also runs efficiently for the sample programs.
Scot Anderson, Peter Z. Revesz
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Psychometric Testing of the Chinese Version of the Decisional Balance Scale (CDBS)
Health Education & Behavior, 2006The purpose of this study was to conduct psychometric testing on the Chinese version of the decisional balance scale (CDBS) with Taiwanese seventh, eighth,and ninth graders who were recruitedfrom the Taipei metropolitan area. A random cluster sampling method was used with 554 adolescents between the ages of 13 and 17 years.
Chen, Huey Shys +2 more
openaire +3 more sources