CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy
Theranostics, 2018 Rationale: Sustained cardiac hypertrophy often leads to heart failure (HF). Understanding the regulation of cardiomyocyte growth is crucial for the treatment of adverse ventricular remodeling and HF. Cell division cycle 20 (CDC20) is an anaphase-promoting complex activator that is essential for cell division and tumorigenesis, but the role of CDC20 in ...
Xie, Yun-Peng +7 more
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Supplementary Figure Legends 1-7 from Functional Interaction between BubR1 and Securin in an Anaphase-Promoting Complex/Cyclosome<sup>Cdc20</sup>–Independent Manner [PDF]
, 2023 Hyunsoo Kim +8 more
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Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition [PDF]
, 2010 Sheena D’Arcy +3 more
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APC/C-Cdc20 mediates deprotection of centromeric cohesin at meiosis II in yeast [PDF]
, 2017 Katarzyna Jonak +6 more
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Cell Reports, 2014 Summary: Downregulation of the schizophrenia-associated gene DISC1 and its interacting protein FEZ1 positively regulates dendrite growth in young neurons.
Yasuhito Watanabe +2 more
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Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance [PDF]
, 2015 Bin Li +13 more
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CDC20 and CCNB1 Overexpression as Prognostic Markers in Bladder Cancer
DiagnosticsBackground: Bladder cancer (BC) is one of the ten most common cancers worldwide, with a high recurrence rate and significant variation in clinical outcomes based on tumor grade and stage.
Hatice Sevim Nalkiran +5 more
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Modelling Cell Cycle using Different Levels of Representation
, 2009 Understanding the behaviour of biological systems requires a complex setting of in vitro and in vivo experiments, which attracts high costs in terms of time and resources.
Antonio Cerone +3 more
core +2 more sources
The Bub1–Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation
Nature Communications, 2016 The mitotic checkpoint complex (MCC) inhibits the anaphase-promoting complex (APC/C) bound to Cdc20 in response to spindle defects. Here, the authors show that Bub1-Plk1-mediated phosphorylation of Cdc20 constitutes a parallel, non-redundant APC/C ...
Luying Jia, Bing Li, Hongtao Yu
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