Results 131 to 140 of about 18,977 (237)

CDC20 regulates cardiac hypertrophy via targeting LC3-dependent autophagy

open access: yesTheranostics, 2018
Rationale: Sustained cardiac hypertrophy often leads to heart failure (HF). Understanding the regulation of cardiomyocyte growth is crucial for the treatment of adverse ventricular remodeling and HF. Cell division cycle 20 (CDC20) is an anaphase-promoting complex activator that is essential for cell division and tumorigenesis, but the role of CDC20 in ...
Xie, Yun-Peng   +7 more
openaire   +2 more sources

Supplementary Figure Legends 1-7 from Functional Interaction between BubR1 and Securin in an Anaphase-Promoting Complex/Cyclosome<sup>Cdc20</sup>–Independent Manner [PDF]

open access: gold, 2023
Hyunsoo Kim   +8 more
openalex   +1 more source

Defining the Molecular Basis of BubR1 Kinetochore Interactions and APC/C-CDC20 Inhibition [PDF]

open access: hybrid, 2010
Sheena D’Arcy   +3 more
openalex   +1 more source

Supplementary Figures 1-4 from Functional Interaction between BubR1 and Securin in an Anaphase-Promoting Complex/Cyclosome<sup>Cdc20</sup>–Independent Manner

open access: gold, 2023
Hyunsoo Kim   +8 more
openalex   +1 more source

APC/C-Cdc20 mediates deprotection of centromeric cohesin at meiosis II in yeast [PDF]

open access: hybrid, 2017
Katarzyna Jonak   +6 more
openalex   +1 more source

Dendrite Development Regulated by the Schizophrenia-Associated Gene FEZ1 Involves the Ubiquitin Proteasome System

open access: yesCell Reports, 2014
Summary: Downregulation of the schizophrenia-associated gene DISC1 and its interacting protein FEZ1 positively regulates dendrite growth in young neurons.
Yasuhito Watanabe   +2 more
doaj   +1 more source

Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance [PDF]

open access: bronze, 2015
Bin Li   +13 more
openalex   +1 more source

CDC20 and CCNB1 Overexpression as Prognostic Markers in Bladder Cancer

open access: yesDiagnostics
Background: Bladder cancer (BC) is one of the ten most common cancers worldwide, with a high recurrence rate and significant variation in clinical outcomes based on tumor grade and stage.
Hatice Sevim Nalkiran   +5 more
doaj   +1 more source

Modelling Cell Cycle using Different Levels of Representation

open access: yes, 2009
Understanding the behaviour of biological systems requires a complex setting of in vitro and in vivo experiments, which attracts high costs in terms of time and resources.
Antonio Cerone   +3 more
core   +2 more sources

The Bub1–Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation

open access: yesNature Communications, 2016
The mitotic checkpoint complex (MCC) inhibits the anaphase-promoting complex (APC/C) bound to Cdc20 in response to spindle defects. Here, the authors show that Bub1-Plk1-mediated phosphorylation of Cdc20 constitutes a parallel, non-redundant APC/C ...
Luying Jia, Bing Li, Hongtao Yu
doaj   +1 more source

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