Accumulation of Mad2–Cdc20 complex during spindle checkpoint activation requires binding of open and closed conformers of Mad2 in Saccharomyces cerevisiae [PDF]
, 2006 Luigi Nezi +5 more
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Cell Cycle Control in Eukaryotes: a BioSpi model [PDF]
, 2003 This paper presents a stochastic model of the cell cycle control in eukaryotes. The framework used is based on stochastic process algebras for mobile systems. The automatic tool used in the simulation is the BioSpi. We compare our approach with classical
Lecca, Paola, Priami, Corrado
core
Cyclin destruction in mitosis: a crucial task of Cdc20
FEBS Letters, 2002 Proteolytic destruction of cyclins is a fundamental process for cell division. At the end of mitosis, degradation of mitotic cyclins results in the inactivation of cyclin‐dependent kinases. Cyclin proteolysis is triggered by the anaphase‐promoting complex/cyclosome (APC/C), a multi‐subunit complex which contains ubiquitin ligase activity.
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Inhibition of Cell Survival by Curcumin Is Associated with Downregulation of Cell Division Cycle 20 (Cdc20) in Pancreatic Cancer Cells [PDF]
, 2017 Yu Zhang +5 more
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Different Functionality of Cdc20 Binding Sites within the Mitotic Checkpoint Complex [PDF]
, 2017 Katharina Sewart, Silke Hauf
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Calcineurin promotes APC/C activation at meiotic exit by acting on both XErp1 and Cdc20 [PDF]
, 2018 Andreas Heim +2 more
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WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis
Journal of Advanced ResearchIntroduction: Acute kidney injury (AKI) is associated with high morbidity and mortality rates. The molecular mechanisms underlying AKI are currently being extensively investigated.
Ran You +12 more
doaj +1 more source
Chromobox 4 (CBX4) promotes tumor progression and stemness via activating CDC20 in gastric cancer [PDF]
, 2022 Wen Li +5 more
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STEM-11MECHANISMS OF CDC20-ANAPHASE-PROMOTING COMPLEX ACTION IN HUMAN GLIOBLASTOMA STEM-LIKE CELLS [PDF]
, 2015 Amit D. Gujar +5 more
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Biallelic mutations in CDC20 cause female infertility due to oocyte maturation abnormality
Gynecological EndocrinologyOocyte maturation arrest (OMA) may occur at different stages, including the germinal vesicle (GV), metaphase I (MI), and metaphase II (MII). A total maturation arrest of human oocytes is rarely observed during in vitro fertilization (IVF).
Guangzhong Jiao +4 more
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