The Bub1–Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation
The mitotic checkpoint complex (MCC) inhibits the anaphase-promoting complex (APC/C) bound to Cdc20 in response to spindle defects. Here, the authors show that Bub1-Plk1-mediated phosphorylation of Cdc20 constitutes a parallel, non-redundant APC/C ...
Luying Jia, Bing Li, Hongtao Yu
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Direct Binding of CDC20 Protein Family Members Activates the Anaphase-Promoting Complex in Mitosis and G1 [PDF]
Guowei Fang +2 more
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The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores [PDF]
Gang Zhang, Jakob Nilsson
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Cortex, a Drosophila gene required to complete oocyte meiosis, is a member of the Cdc20/fizzy protein family [PDF]
T. Ming Chu +3 more
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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation [PDF]
Guowei Fang +2 more
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WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis
Introduction: Acute kidney injury (AKI) is associated with high morbidity and mortality rates. The molecular mechanisms underlying AKI are currently being extensively investigated.
Ran You +12 more
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Cell Cycle Control in Eukaryotes: a BioSpi model [PDF]
This paper presents a stochastic model of the cell cycle control in eukaryotes. The framework used is based on stochastic process algebras for mobile systems. The automatic tool used in the simulation is the BioSpi. We compare our approach with classical
Lecca, Paola, Priami, Corrado
core
Identification of an oncogenic role of centromere protein M in non-small cell lung cancer via CDC20/MYBL2/Wnt signals [PDF]
Ling Juan Wu +4 more
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