Results 161 to 170 of about 20,775 (267)

The Bub1–Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation

open access: yesNature Communications, 2016
The mitotic checkpoint complex (MCC) inhibits the anaphase-promoting complex (APC/C) bound to Cdc20 in response to spindle defects. Here, the authors show that Bub1-Plk1-mediated phosphorylation of Cdc20 constitutes a parallel, non-redundant APC/C ...
Luying Jia, Bing Li, Hongtao Yu
doaj   +1 more source

WWP2 deletion aggravates acute kidney injury by targeting CDC20/autophagy axis

open access: yesJournal of Advanced Research
Introduction: Acute kidney injury (AKI) is associated with high morbidity and mortality rates. The molecular mechanisms underlying AKI are currently being extensively investigated.
Ran You   +12 more
doaj   +1 more source

Cell Cycle Control in Eukaryotes: a BioSpi model [PDF]

open access: yes, 2003
This paper presents a stochastic model of the cell cycle control in eukaryotes. The framework used is based on stochastic process algebras for mobile systems. The automatic tool used in the simulation is the BioSpi. We compare our approach with classical
Lecca, Paola, Priami, Corrado
core  

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