Results 31 to 40 of about 20,500 (223)
Knockdown of CDC20 promotes adipogenesis of bone marrow-derived stem cells by modulating β-catenin
Stem Cell Research & Therapy, 2022 Background Bone is a rigid organ that provides physical protection and support to vital organs of the body. Bone loss disorders are commonly associated with increased bone marrow adipose tissue.
Yangge Du +3 more
doaj +1 more source
The potential role of CDC20 in tumorigenesis, cancer progression and therapy: A narrative review
Medicine, 2023 The cell division cycle 20 homologue (CDC20) is known to regulate the cell cycle. Many studies have suggested that dysregulation of CDC20 is associated with various pathological processes in malignant solid tumors, including tumorigenesis, progression ...
F. Xian +4 more
semanticscholar +1 more source
Correction for Deng et al., The <i>Arabidopsis</i> BUB1/MAD3 family protein BMF3 requires BUB3.3 to recruit CDC20 to kinetochores in spindle assembly checkpoint signaling. [PDF]
Proc Natl Acad Sci U S Aeuropepmc +3 more sources
Effects of SP600125 on Proliferation and Invasion of Human Cervical Cancer HeLa Cells
Zhongliu Fangzhi Yanjiu, 2022 Objective To investigate the effect of SP600125 on the proliferation, cell cycle, apoptosis and invasion of human cervical cancer HeLa cells. Methods CCK-8 method was used to detect the proliferation of HeLa cells treated with different concentrations of
MO Yanxiu +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2023 Objectives An acute injury is often accompanied by tissue regeneration. In this process, epithelial cells show a tendency of cell proliferation under the induction of injury stress, inflammatory factors, and other factors, accompanied by a temporary ...
Jihang Shi +17 more
doaj +1 more source
The Role of the APC/C and Its Coactivators Cdh1 and Cdc20 in Cancer Development and Therapy
Frontiers in Genetics, 2022 To sustain genomic stability by correct DNA replication and mitosis, cell cycle progression is tightly controlled by the cyclic activity of cyclin-dependent kinases, their binding to cyclins in the respective phase and the regulation of cyclin levels by ...
C. Greil, M. Engelhardt, R. Wäsch
semanticscholar +1 more source
Anticancer Research, 2022 Background/Aim: The functions of the specific genes involved in the three types of breast cancer (BC) are unclear. Materials and Methods: A total of 53,805 genes were assessed from the RNA-sequencing database of BC cells and classified into those ...
Christine Song +3 more
semanticscholar +1 more source
Regulated degradation of the APC coactivator Cdc20
Cell Division, 2010 Background Cdc20 is a highly conserved activator of the anaphase-promoting complex (APC), promoting cell-cycle-regulated ubiquitination and proteolysis of a number of critical cell-cycle-regulatory targets including securin and mitotic cyclins. APC-Cdc20
Robbins Jonathan A, Cross Frederick R
doaj +1 more source
Modeling Dual Pathways for the Metazoan Spindle Assembly Checkpoint [PDF]
, 2006 Using computational modelling, we investigate mechanisms of signal transduction focusing on the spindle assembly checkpoint where a single unattached kinetochore is able to signal to prevent cell cycle progression.
Acquaviva +29 more
core +3 more sources
International Journal on Biological Sciences, 2021 Purpose: The incidence of hepatocellular carcinoma (HCC) is extremely high, and China accounts for approximately 50% of global liver cancer cases.
Shuai Zhao +11 more
semanticscholar +1 more source