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FGD3 mediates lytic cell death, enhancing efficacy and immunogenicity of chemotherapy agents in breast cancer. [PDF]
Zhu J +13 more
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A Rho GTPase-effector ensemble governs cell migration behavior. [PDF]
Lee H +13 more
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A Meta-analysis to Identify Common Key Genes Across Ageing, Alzheimer's and Parkinson's Diseases. [PDF]
Chaurasiya M +3 more
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Small Rho GTPase Family Member Cdc42 and Its Role in Neuronal Survival and Apoptosis
Noelle Punessen
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Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix. [PDF]
Iwata W +8 more
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Depletion of LINC01133 from cancer-associated fibroblasts exacerbates the progression of gastric adenocarcinoma. [PDF]
Liang X +23 more
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Cdc42: Role in Cancer Management
Chemical Biology & Drug Design, 2015Contribution of Cdc42, a member of Rho family, has been characterized for the beginning of variety of cellular responses including cellular transformation, cell division, cell invasion, migration, invadopodia formation, enzyme activity, filopodia formation, and cell polarity in cells. Deregulation of Cdc42 can alter the normal functioning of the cells,
Muhammad Imran, Qadir +2 more
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NMR assignment of Cdc42(T35A), an active Switch I mutant of Cdc42
Biomolecular NMR Assignments, 2007Cdc42(T35A) is an active construct of Cdc42, a Ras GTPase involved in signal transduction, containing a single-point mutation in an important effector-binding region. We determined the backbone and side chain resonance assignments of (13)C,(15)N-labelled Cdc42(T35A) from E. coli.
Adams, Paul D., Oswald, Robert E.
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