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Cdc42: An important regulator of neuronal morphology
The International Journal of Biochemistry & Cell Biology, 2012Regulation of neuronal morphology and activity-dependent synaptic modifications involves reorganization of the actin cytoskeleton. Dynamic changes of the actin cytoskeleton in many cell types are controlled by small GTPases of the Rho family, such as RhoA, Rac1 and Cdc42.
Chen, Chen +2 more
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Cdc42 Protects the EGF Receptor
Science Signaling, 2003It is thought that altered receptor turnover can account for increased expression of the cell surface receptor for epidermal growth factor (EGF) observed in some human cancers. Wu et al. have identified a signaling pathway that contributes to this phenotype.
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A brain serine/threonine protein kinase activated by Cdc42 and Rac1
Nature, 1994E. Manser +4 more
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Full activation of WASP, not N-WASP, by Cdc42 and PIP2 requires Cdc42 prenylation
Biophysical Journal, 2023Souvik Dey, Huan-Xiang Zhou
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