Results 61 to 70 of about 6,916 (192)
Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization
The FEBS Journal, EarlyView.PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe +6 more
wiley +1 more source
Multidimensional Militarisation, Evidence From Mexico's War on Drugs
International Social Science Journal, EarlyView.ABSTRACT This article documents different dimensions of militarisation observed in Mexico since the start of the war on drugs. It argues that militarisation is a multidirectional phenomenon that is characterised by rationales that justify the use of illegal means to address complex issues, promising expediency and efficiency but rarely delivering on it.
Agustin Hernandez Berea
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Instrumented assessment of gait disturbance in PMM2-CDG adults: a feasibility analysis
Orphanet Journal of Rare DiseasesBackground Congenital disorders of glycosylation (CDG) are genetic diseases caused by impaired synthesis of glycan moieties linked to glycoconjugates.
Lara Cirnigliaro +10 more
doaj +1 more source
Analytical Science Advances, Volume 7, Issue 2, December 2026.ABSTRACT A validated analytical workflow is presented for determining total and bioaccessible concentrations of regulated elements in tattoo inks, addressing the lack of harmonized protocols for comparing extraction approaches in complex matrices. Although current legislation defines limits for soluble fractions of selected metals, it does not specify ...
Maria Luisa Astolfi +3 more
wiley +1 more source
SMART: Speedy Measurement of Arabidopsis Rosette Traits
The Plant Phenome Journal, Volume 9, Issue 1, December 2026.Abstract Most computer vision‐ and machine learning‐based plant phenotyping systems compute traits such as shape and size rather than the color distribution of the plant surface, even though color can provide important insights into plant physiology. Therefore, we developed Speedy Measurement of Arabidopsis Rosette Traits (SMART), an open‐source plant ...
Suxing Liu +5 more
wiley +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk +39 more
wiley +1 more source
Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers
International Journal of Cancer, Volume 159, Issue 7, Page 1663-1668, 1 October 2026.BRCA1 and BRCA2 pathogenic germline variant (PGV) carriers may be at increased risk of gastric cancer (GC), especially in the case of prior or active Helicobacter pylori (Hp) infection. The extent to which Hp influences BRCA1 and BRCA2‐associated GC remains uncertain. Here, the authors evaluated plasma samples from a U.S. cohort of BRCA1, BRCA2, PALB2,
Kole H. Buckley +12 more
wiley +1 more source
Revisiting the immunopathology of congenital disorders of glycosylation: an updated review
Frontiers in ImmunologyGlycosylation is a critical post-translational modification that plays a pivotal role in several biological processes, such as the immune response.
Carlota Pascoal +25 more
doaj +1 more source
Physiotherapy Research International, Volume 31, Issue 4, October 2026.ABSTRACT Background and Purpose The Canadian 24‐Hour Movement Guidelines integrate recommendations on physical activity (PA), sedentary behavior (SB), and sleep. Individuals in cardiac rehabilitation programs (CRPs) have specific characteristics that may influence adherence to these 24‐Hour Movement Guidelines and their relationship with quality of ...
Júlio César de Ávila Soares +6 more
wiley +1 more source