Results 201 to 210 of about 405,232 (337)

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Tissue Gene Expression Analysis Using Arrayed Normalized cDNA Libraries [PDF]

open access: hybrid, 2000
Holger Eickhoff   +12 more
openalex   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

open access: yesAdvanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang   +11 more
wiley   +1 more source

cDNA Library Enrichment of Full Length Transcripts for SMRT Long Read Sequencing. [PDF]

open access: yesPLoS One, 2016
Cartolano M   +4 more
europepmc   +1 more source

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

open access: yesAdvanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang   +10 more
wiley   +1 more source

Partial results of the construction of cDNA library of Megalopyge albicolis [PDF]

open access: yesBMC Proc, 2014
Mazur T   +6 more
europepmc   +1 more source

Chemiluminescent Detection of Sequential DNA Hybridizations to High-Density, Filter-Arrayed cDNA Libraries: A Subtraction Method for Novel Gene Discovery

open access: gold, 1999
David B. Guiliano   +12 more
openalex   +1 more source

Unveiling Salt Tolerance Mechanisms in Plants: Integrating the KANMB Machine Learning Model With Metabolomic and Transcriptomic Analysis

open access: yesAdvanced Science, EarlyView.
Salt stress endangers coastal cereal crops, requiring resilient crop solutions. This study employs machine learning (KANMB) to analyze multi‐omics data from halophyte Spartina alterniflora, revealing 226 salt‐stress biomarkers and linking them to tolerance pathways. The MYB gene SaMYB35 regulates flavonoid biosynthesis under salinity.
Shoukun Chen   +7 more
wiley   +1 more source

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