Results 211 to 220 of about 149,367 (278)

Relationship between age and severity of cognitive impairment at diagnosis for early‐onset and late‐onset Alzheimer's disease: Comparison of LEADS and ADNI

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
INTRODUCTION Recent work has identified unique cognitive profiles for early‐onset Alzheimer's disease (EOAD) relative to late‐onset Alzheimer's disease (LOAD), however, examination has been limited in determining whether the association between age and cognitive severity at presentation also differs across conditions.
Dustin B. Hammers, Ani Eloyan, Maryanne Thangarajah, Alexander Taurone, Sujuan Gao, Laurel Beckett, Kala Kirby, Jeffrey L. Dage, Kelly Nudelman, Paul Aisen, Rema Reman, Prashanthi Vemuri, Renaud La Joie, Alexandra Touroutoglou, Alireza Atri, David Clark, Gregory S. Day, Ranjan Duara, Neill R. Graff‐Radford, Lawrence S. Honig, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Kyle Womack, Erik Musiek, Chiadi U. Onyike, Meghan Riddle, Ian Grant, Emily Rogalski, Erik C. B. Johnson, Steven Salloway, Sharon J. Sha, Raymond Scott Turner, Thomas S. Wingo, David A. Wolk, Maria C. Carrillo, Bradford C. Dickerson, Gil D. Rabinovici, Liana G. Apostolova, LEADS Consortium, for the Alzheimer's Disease Neuroimaging Initiative   +40 more
wiley   +1 more source

Hidden in Plain Sight: Low Tacrolimus Metabolism Doubles Kidney Transplant Failure and Drives Infection Related Mortality. [PDF]

Transpl Int
Süsal C, Döhler B, Demir E, Ibrahim W, Askar M.   +4 more
europepmc   +1 more source

AI‐enhanced Centiloid quantification of amyloid PET images

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The Centiloid scale is the standard for amyloid (Aβ) PET quantification in research and clinical settings. However, variability between tracers and scanners remains a challenge. METHODS This study introduces DeepSUVR, a deep learning method to correct Centiloid quantification, by penalizing implausible longitudinal trajectories ...
Pierrick Bourgeat, Jurgen Fripp, Leo Lebrat, Ying Xia, Azadeh Feizpour, Timothy Cox, Georgios Zisis, Ashley Gillman, Manu S. Goyal, Duygu Tosun, Tammie LS. Benzinger, Pamela LaMontagne, Michael Breakspear, Michelle K. Lupton, Cathy Short, Robert Adam, Joanne S. Robertson, Reisa Sperling, Sid E. O'Bryant, Sterling C. Johnson, Clifford R. Jack Jr, Christopher G. Schwarz, Frederik Barkhof, Gill Farrar, Ariane Bollack, Lyduine E. Collij, Susan Landau, Robert Koeppe, for the Alzheimer's Disease Neuroimaging Initiative, OASIS3, the A4/LEARN Study Team, the AMYPAD consortium, The Health and Aging Brain Study (HABS‐HD) Study Team, Mayo Clinic Study of Aging, WRAP, ADNI‐DOD, PISA, ADNeT, the AIBL research group, John C. Morris, Michael W. Weiner, Victor L. Villemagne, Colin L. Masters, Christopher C. Rowe, Vincent Dore   +44 more
wiley   +1 more source

Enhanced Weathering for CDR

Assessment and full characterisation of Enhanced Weathering as CDR solution.
openaire   +1 more source

Falls predict faster progression to Alzheimer's dementia

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION In preclinical Alzheimer's disease (AD), amyloid accumulates in the brain while individuals remain cognitively unimpaired (Clinical Dementia Rating® [CDR] = 0). Differentiating trajectories of healthy aging and preclinical AD is challenging as both are associated with age‐related impairments (e.g., falls).
Audrey A. Keleman, Melody Li, Julie K. Wisch, Rebecca M. Bollinger, Melissa J. Krauss, Elizabeth A. Grant, Tammie L. S. Benzinger, Beau M. Ances, John C. Morris, Susan L. Stark   +9 more
wiley   +1 more source

Integrated structural and functional brain imaging reveals biomarkers of disease activity in Crohn's disease. [PDF]

BMC Gastroenterol
Bao C, Xu S, Wu L, Zhu X, Wang D, Zhang Z, Qu C, Shi Y, Zeng X, Zhong J, Zhang J, Wang S, Zheng R, Jin X, Wang H, Liu H, Wu H.   +16 more
europepmc   +1 more source

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Sleep disruption, particularly loss of slow‐wave sleep (SWS), is common in Alzheimer's disease (AD), but its neurobiological underpinnings remain unclear. We investigated whether locus coeruleus (LC) integrity relates to SWS across the AD continuum and whether sex and perivascular spaces (PVSs) modify these associations.
Neus Falgàs, Núria Tort‐Colet, Isabel Martín‐Sobrino, Gerard Mayà, Marta Peña‐González, Salvatore Rudilosso, Carles Gaig, Beatriz Bosch, Aurora Arqueros, Agnès Pérez‐Millan, Adrià Tort‐Merino, Guadalupe Fernández‐Villullas, Gerard Piñol‐Ripoll, Mircea Balasa, Albert Lladó, Manuel Morales Ruiz, Emma Muñoz‐Moreno, Oriol Grau‐Rivera, Alex Iranzo, Lea T. Grinberg, Raquel Sánchez‐Valle   +20 more
wiley   +1 more source

Harmonizing neuropsychological test data across prospective studies

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) research relies on large datasets and advanced statistical models. However, individual population studies often lack sufficient sample size for conclusive results. Harmonizing cognitive test data across studies can address this gap, despite differences in testing protocols.
Rosita Shishegar, James D. Doecke, Yen Ying Lim, Pierrick Bourgeat, Vincent Dore, Bhargav Tallapragada, Simon M. Laws, Tenielle Porter, Samantha Burnham, Azadeh Feizpour, Ashley Gillman, Michael Weiner, Jason Hassenstab, Christopher C. Rowe, Victor L. Villemagne, Colin L. Masters, Jurgen Fripp, Hamid Sohrabi, Paul Maruff, for the Alzheimer's Disease Neuroimaging Initiative, OASIS‐3, and the Australian Imaging Biomarkers and Lifestyle flagship study of ageing   +21 more
wiley   +1 more source

Concurrent Calcium and Magnesium Determination by Ion Chromatography: An Approach to Avoid Interferences That Compromise Analysis

Biomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT To evaluate phosphate‐binding by calcium succinate and combinations of calcium and magnesium salts, ion chromatography (IC) methods were developed and validated for the determination of calcium and magnesium across the pH range in the human gastrointestinal tract (pH 1.2–6.8). Separation was achieved on a Dionex IC system using a Dionex IonPac
Deanna Nelson, G. Dean Marbury
wiley   +1 more source