Results 31 to 40 of about 207,846 (301)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Risk Spillovers in Oil-Related CDS, Stock and Credit Markets [PDF]
This paper examines risk transmission and migration among six US measures of credit and market risk during the full period 2004-2011 period and the 2009-2011 recovery subperiod, with a focus on four sectors related to the highly volatile oil price. There
Michael McAleer +3 more
core +6 more sources
Storehouse and sanctuary: the role of Brazil in world food security
Fronteiras: Journal of Social, Technological and Environmental Science, 2013 Natural endowments such as land availability, abundant water, fertile soils, and favorable climate combined with decreasing population growth place Brazil as the leading force in world food production.
James Augusto Pires Tiburcio +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Desenvolvimento e Meio Ambiente, 2018 Urban areas are responsible for environmental problems at the global scale and are also vulnerable to local and global environmental impacts.
Patricia dos Santos Mesquita +1 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
High Precision Roll/Yaw Attitude Stabilization for Flexible communication satellite
Algerian Journal of Signals and Systems, 2018 The aim of this paper is to realize high-precision attitude stabilization for roll/yaw axes of flexible communication satellite while attenuate the effects of the elastic vibrations and multiple disturbances such as solar radiation and model ...
J. E Benmansour, B. Khouane, R. Rima
doaj +1 more source
Финансы: теория и практика, 2022 The subject of the research is the influence of the debt burden of state-owned companies on the dynamics of Russia’s corporate external debt. The relevance is due to the unprecedented combination of sanctions in 2022, which created default risks of ...
S. A. Perekhod +3 more
doaj +1 more source