Results 41 to 50 of about 207,846 (301)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
CDS wide slit time-series of EUV coronal bright points [PDF]
, 2004 Wide slit (90" x 240" ) movies of four Extreme Ultraviolet coronal bright points (BPs) obtained with the Coronal Diagnostic Spectrometer (CDS) on board the Solar and Heliospheric Observatory (SoHO) have been inspected.
V. M. Nakariakov +7 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Kredi Temerrüt Swapları ve Makroekonomik Değişkenler Arasındaki İlişkinin Analizi
Ekonomi, Politika & Finans Araştırmaları Dergisi, 2023 Kredi Temerrüt Swap (CDS) primleri, ülkelerin kredi riskinin bir göstergesi olarak kabul edilmektedir. Bu çalışmada Türkiye’nin CDS primlerini etkileyen makroekonomik faktörlerin belirlenmesi amaçlanmaktadır.
Ayşegül İşcanoğlu Çekiç +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Kredi Temerrüt Takası (CDS) ve Borsa Endeks İlişkisi: BRICS Ülkeleri Üzerine Bir Araştırma
Ekonomi, Politika & Finans Araştırmaları Dergisi, 2021 Kredi temerrüt takasları (CDS), kredi riskinin borç veren tarafından daha düşük bir maliyetle karşılanmasını sağlamaktadır. Yüksek CDS primleri beraberinde yüksek borçlanma maliyetlerini getirmektedir.
Ali Bayrakdaroğlu, Çağatay Mirgen
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Screen printed layers of cds for solar cells [PDF]
, 1988 It is generally accepted nowadays that a significant cost reduction in terrestrial solar cell application could be brought about by investigating alternative fabrication techniques for solar cells.
Faidah, A.S, Faidah, Adel Saleh
core