Results 21 to 30 of about 8,393 (214)

Characterization and Pharmacological Inhibition of the Pore-Forming Clostridioides difficile CDTb Toxin

open access: yesToxins, 2021
The clinically highly relevant Clostridioides (C.) difficile releases several AB-type toxins that cause diseases such as diarrhea and pseudomembranous colitis.
Katharina Ernst   +7 more
doaj   +1 more source

Mechanical Behavior of Transparent Spinel Fabricated by Spark Plasma Sintering

open access: yesCeramics, 2023
In this work, a transparent nanostructured ceramic magnesium aluminate spinel (MgAl2O4) was fabricated by Spark Plasma Sintering (SPS) from commercial spinel nano-powders at different temperatures (1300, 1350 and 1400 °C).
Khadidja Hoggas   +6 more
doaj   +1 more source

Is Fecal Leukocyte Test a good predictor of Clostridium difficile associated diarrhea?

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2006
Background Fecal leukocyte test (FLT) is widely used to screen for invasive diarrheas including C. difficile associated diarrhea (CDAD), which account for more than 25 % of all antibiotic associated diarrhea.
Sheth Ankur   +2 more
doaj   +1 more source

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

open access: yes, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon   +9 more
core   +2 more sources

COVI3D: Automatic COVID-19 CT Image-Based Classification and Visualization Platform Utilizing Virtual and Augmented Reality Technologies

open access: yesDiagnostics, 2022
Recently many studies have shown the effectiveness of using augmented reality (AR) and virtual reality (VR) in biomedical image analysis. However, they are not automating the COVID level classification process.
Samir Benbelkacem   +7 more
doaj   +1 more source

Sequence Variability of P2-Like Prophage Genomes Carrying the Cytolethal Distending Toxin V Operon in Escherichia coli O157 [PDF]

open access: yes, 2013
Cytolethal distending toxins (CDT) are potent cytotoxins of several Gram-negative pathogenic bacteria, including Escherichia coli, in which five types (CDT-I to CDT-V) have been identified so far.
Allué-Guardia   +44 more
core   +1 more source

Tailored Cyclodextrin Pore Blocker Protects Mammalian Cells from Clostridium difficile Binary Toxin CDT

open access: yesToxins, 2014
Some Clostridium difficile strains produce, in addition to toxins A and B, the binary toxin Clostridium difficile transferase (CDT), which ADP-ribosylates actin and may contribute to the hypervirulence of these strains.
Maurice Roeder   +5 more
doaj   +1 more source

The Binary Toxin of Clostridioides difficile Alters the Proteome and Phosphoproteome of HEp-2 Cells

open access: yesFrontiers in Microbiology, 2021
Clostridioides difficile is a major cause of nosocomial infection worldwide causing antibiotic-associated diarrhea and some cases are leading to pseudomembranous colitis. The main virulence factors are toxin A and toxin B.
Florian Stieglitz   +4 more
doaj   +1 more source

The Cell-Cycle Regulatory Protein p21CIP1/WAF1 Is Required for Cytolethal Distending Toxin (Cdt)-Induced Apoptosis. [PDF]

open access: yes, 2020
The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) induces lymphocytes to undergo cell-cycle arrest and apoptosis; toxicity is dependent upon the active Cdt subunit, CdtB.
Boesze-Battaglia, Kathleen   +4 more
core   +2 more sources

Systematic Derivation for Quadrature Oscillators Using CCCCTAs [PDF]

open access: yes, 2015
According to 16 nullor-mirror models of the current-controlled current conveyor transconductance amplifier (CCCCTA) and using nodal admittance matrix (NAM) expansion method, three different classes of the double-mode quadrature oscillators employed ...
Li, Y. A.
core   +2 more sources

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